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Transmission of hep...
Transmission of hepatitis C virus by transfusion in Orebro County, Sweden, 1990-1992
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- Norda, Rut (författare)
- Karolinska Institutet
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- Duberg, Ann-Sofi, 1957- (författare)
- Departments of Infectious Diseases, Örebro Medical Center Hospital, Örebro, Sweden
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- Sönnerborg, Anders (författare)
- Departments of Clinical Microbiology and Immunology, Örebro Medical Center Hospital, Örebro, Sweden
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- Olcén, Per (författare)
- Departments of Division of Clinical Virology, Karolinska Institutet, Huddinge University Hospital, Huddinge, Sweden
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(creator_code:org_t)
- 2009-07-08
- 1995
- Engelska.
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Ingår i: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 27:5, s. 449-452
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- A retrospective study of hepatitis C virus (HCV) transmission by transfusion was conducted in Orebro county. Out of the 7,900 active, registered blood donors, 21 repeatedly anti-HCV reactive (RIVA 2 positive or indeterminate) donors were diagnosed. Their 84 recipients from January 1990 through June 1992 were identified and 41 (49%) were alive in December 1992. A total of 13 anti-HCV reactive (RIBA 2 positive or indeterminate) were diagnosed in 39 investigated recipients. Of these 11 were previously undiagnosed, and seven were HCV RNA-positive. In the donor population 1.03% were anti-HCV-positive by ELISA, but only 0.09% were RIBA and HCV RNA-positive. In 1990, 0.06% of the blood components came from the HCV RNA-positive donors, and none during the first 6 months of 1992. In order to identify transfusion-transmitted HCV infections that took place before the introduction of tests for anti-HCV antibodies, patients with a history of transfusion and symptoms and signs of liver dysfunction or damage should be thoroughly tested.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Adult; Aged; Blood Donors; Blood Transfusion; Female; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; Human; Male; Middle Age; Retrospective Studies; RNA
- Viral; Support
- Non-U.S. Gov't; Sweden
- Infektionssjukdomar
- Infectious Diseases
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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