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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03336naa a2200349 4500 | |
| 001 | oai:DiVA.org:oru-42602 | |
| 003 | SwePub | |
| 008 | 150212s2014 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-426022 URI |
| 024 | 7 | a https://doi.org/10.1155/2014/2371072 DOI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Stenberg, Reidun,d 1954-u Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Department of Pediatrics, Örebro University Hospital, Örebro, Sweden; Centre for Rehabilitation Research, Region Örebro County, Örebro, Sweden4 aut0 (Swepub:oru)rsg |
| 245 | 1 0 | a Anti-transglutaminase 6 antibodies in children and young adults with cerebral palsy |
| 264 | 1 | b Hindawi Publishing Corporation,c 2014 |
| 338 | a print2 rdacarrier | |
| 520 | a Objectives: We have previously reported a high prevalence of gluten-related serological markers (GRSM) in children and young adults with cerebral palsy (CP). The majority had no enteropathy to suggest coeliac disease (CD). Antibodies against transglutaminase 6 (anti-TG6) represent a new marker associated with gluten-related neurological dysfunction. The aim of this study was to investigate the prevalence of anti-TG6 antibodies in this group of individuals with an early neurological injury resulting in CP.Materials and Methods: Sera from 96 patients with CP and 36 controls were analysed for IgA/IgG class anti-TG6 by ELISA.Results: Anti-TG6 antibodies were found in 12/96 (13%) of patients with CP compared to 2/36 (6%) in controls. The tetraplegic subgroup of CP had a significantly higher prevalence of anti-TG6 antibodies 6/17 (35%) compared to the other subgroups and controls. There was no correlation of anti-TG6 autoantibodies with seropositivity to food proteins including gliadin.Conclusions: An early brain insult and associated inflammation may predispose to future development of TG6 autoimmunity. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
| 700 | 1 | a Hadjivassiliou, Mariosu Department of Neurology and Department of Neuroradiology,The Royal Hallamshire Hospital, Sheffield, UK4 aut |
| 700 | 1 | a Aeschlimann, Pascaleu Matrix Biology & Tissue Repair Research Unit, College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff, UK4 aut |
| 700 | 1 | a Hoggard, Nigelu Department of Neurology and Department of Neuroradiology,The Royal Hallamshire Hospital, Sheffield, UK4 aut |
| 700 | 1 | a Aeschlimann, Danielu Matrix Biology & Tissue Repair Research Unit, College of Biomedical and Life Sciences, School of Dentistry, Cardiff University, Cardiff, UK4 aut |
| 710 | 2 | a Örebro universitetb Institutionen för hälsovetenskap och medicin4 org |
| 773 | 0 | t Autoimmune Diseasesd : Hindawi Publishing Corporationx 2090-0422x 2090-0430 |
| 856 | 4 | u https://doi.org/10.1155/2014/237107y Fulltext |
| 856 | 4 | u http://downloads.hindawi.com/journals/ad/2014/237107.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-42602 |
| 856 | 4 8 | u https://doi.org/10.1155/2014/237107 |
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