onr:"swepub:oai:DiVA.org:oru-48977"
Sökning: onr:"swepub:oai:DiVA.org:oru-48977" > Obesity and risk fo...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04894naa a2200601 4500 | |
| 001 | oai:DiVA.org:oru-48977 | |
| 003 | SwePub | |
| 008 | 160306s2006 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-80531 | |
| 009 | oai:prod.swepub.kib.ki.se:1940059 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-489772 URI |
| 024 | 7 | a https://doi.org/10.1681/ASN.20050606382 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-805312 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19400592 URI |
| 040 | a (SwePub)orud (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Ejerblad, Elisabethu Uppsala universitet,Institutionen för medicinska vetenskaper,Verksamhetsområde hematologi,Blodsjukdomar4 aut0 (Swepub:uu)eleje020 |
| 245 | 1 0 | a Obesity and risk for chronic renal failure |
| 264 | 1 | a Philadelphia, USA :b Lippincott Williams & Wilkins,c 2006 |
| 338 | a print2 rdacarrier | |
| 520 | a Few large-scale epidemiologic studies have quantified the possible link between obesity and chronic renal failure (CRF). This study analyzed anthropometric data from a nationwide, population-based, case-control study of incident, moderately severe CRF. Eligible as cases were all native Swedes who were aged 18 to 74 yr and had CRF and whose serum creatinine for the first time and permanently exceeded 3.4 mg/dl (men) or 2.8 mg/dl (women) during the study period. A total of 926 case patients and 998 control subjects, randomly drawn from the study base, were enrolled. Face-to-face interviews, supplemented with self-administered questionnaires, provided information about anthropometric measures and other lifestyle factors. Logistic regression models with adjustments for several co-factors estimated the relative risk for CRF in relation to body mass index (BMI). Overweight (BMI>or=25 kg/m2) at age 20 was associated with a significant three-fold excess risk for CRF, relative to BMI<25. Obesity (BMI>or=30) among men and morbid obesity (BMI>or=35) among women anytime during lifetime was linked to three- to four-fold increases in risk. The strongest association was with diabetic nephropathy, but two- to three-fold risk elevations were observed for all major subtypes of CRF. Analyses that were confined to strata without hypertension or diabetes revealed a three-fold increased risk among patients who were overweight at age 20, whereas the two-fold observed risk elevation among those who had a highest lifetime BMI of >35 was statistically nonsignificant. Obesity seems to be an important-and potentially preventable-risk factor for CRF. Although hypertension and type 2 diabetes are important mediators, additional pathways also may exist. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
| 653 | a Adolescent | |
| 653 | a Adult | |
| 653 | a Aged | |
| 653 | a Body Mass Index | |
| 653 | a Case-Control Studies | |
| 653 | a Female | |
| 653 | a Humans | |
| 653 | a Kidney Failure | |
| 653 | a Chronic/*complications/*diagnosis/etiology | |
| 653 | a Male | |
| 653 | a Middle Aged | |
| 653 | a Obesity/*complications | |
| 653 | a Risk | |
| 653 | a Sweden | |
| 700 | 1 | a Fored, C. M.u Karolinska Institutet4 aut |
| 700 | 1 | a Lindblad, Per,d 1953-u Department of Medical Epidemiology and Biostatistics, Karolinska Institute and Karolinsak University Hospital, Stockholm, Sweden; Department of Urology, Sundsvall Hospital, Sundsvall, Sweden4 aut0 (Swepub:oru)pld |
| 700 | 1 | a Fryzek, J.u The International Epidemiology Institute, Rockville, Maryland, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA4 aut |
| 700 | 1 | a McLaughlin, J. K.u The International Epidemiology Institute, Rockville, Maryland, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA4 aut |
| 700 | 1 | a Nyren, O.u Karolinska Institutet4 aut |
| 710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
| 773 | 0 | t Journal of the American Society of Nephrologyd Philadelphia, USA : Lippincott Williams & Wilkinsg 17:6, s. 1695-1702q 17:6<1695-1702x 1046-6673x 1533-3450 |
| 856 | 4 | u https://doi.org/10.1681/ASN.2005060638y Fulltext |
| 856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16641153&dopt=Citation |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-48977 |
| 856 | 4 8 | u https://doi.org/10.1681/ASN.2005060638 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-80531 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1940059 |
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