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Sökning: onr:"swepub:oai:DiVA.org:oru-49813" > Multi-component ass...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006661naa a2200529 4500
001oai:DiVA.org:oru-49813
003SwePub
008160412s2016 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-297373
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-498132 URI
0247 a https://doi.org/10.1038/npjpcrm.2016.102 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2973732 URI
040 a (SwePub)orud (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Jones, Rupert C.u Clinical Trials and Population Studies, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK,Univ Plymouth, Peninsula Sch Med, Clin Trials & Populat Studies, ITTC Bldg N14,Plymouth Sci Pk, Plymouth PL4 8AA, Devon, England.;Univ Plymouth, Peninsula Sch Dent, Clin Trials & Populat Studies, ITTC Bldg N14,Plymouth Sci Pk, Plymouth PL4 8AA, Devon, England.4 aut
2451 0a Multi-component assessment of chronic obstructive pulmonary disease :b an evaluation of the ADO and DOSE indices and the global obstructive lung disease categories in international primary care data sets
264 c 2016-04-07
264 1a London, United Kingdom :b Nature Publishing Group,c 2016
338 a print2 rdacarrier
500 a Funding Agencies:International Primary Care Respiratory Group (IPCRG)Novartis AG, Basel, SwitzerlandREGPICASSO for COPD
520 a Suitable tools for assessing the severity of chronic obstructive pulmonary disease (COPD) include multi-component indices and the global initiative for chronic obstructive lung disease (GOLD) categories. The aim of this study was to evaluate the dyspnoea, obstruction, smoking, exacerbation (DOSE) and the age, dyspnoea, obstruction (ADO) indices and GOLD categories as measures of current health status and future outcomes in COPD patients. This was an observational cohort study comprising 5,114 primary care COPD patients across three databases from UK, Sweden and Holland. The associations of DOSE and ADO indices with (i) health status using the Clinical COPD Questionnaire (CCQ) and St George's Respiratory Questionnaire (SGRQ) and COPD Assessment test (CAT) and with (ii) current and future exacerbations, admissions and mortality were assessed in GOLD categories and DOSE and ADO indices. DOSE and ADO indices were significant predictors of future exacerbations: incident rate ratio was 1.52 (95% confidence intervals 1.46-1.57) for DOSE, 1.16 (1.12-1.20) for ADO index and 1.50 (1.33-1.68) and 1.23 (1.10-1.39), respectively, for hospitalisations. Negative binomial regression showed that the DOSE index was a better predictor of future admissions than were its component items. The hazard ratios for mortality were generally higher for ADO index groups than for DOSE index groups. The GOLD categories produced widely differing assessments for future exacerbation risk or for hospitalisation depending on the methods used to calculate them. None of the assessment systems were excellent at predicting future risk in COPD; the DOSE index appears better than the ADO index for predicting many outcomes, but not mortality. The GOLD categories predict future risk inconsistently. The DOSE index and the GOLD categories using exacerbation frequency may be used to identify those at high risk for exacerbations and admissions.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng
653 a Pulmonary Medicine
653 a Lungmedicin
7001 a Price, Davidu Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK,Univ Aberdeen, Ctr Acad Primary Care, Aberdeen, Scotland.4 aut
7001 a Chavannes, Niels H.u Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands,Leiden Univ, Med Ctr, Dept Publ Hlth & Primary Care, Leiden, Netherlands.4 aut
7001 a Lee, Amanda J.u Medical Statistics Team, Applied Health Sciences, University of Aberdeen, Aberdeen, UK,Univ Aberdeen, Appl Hlth Sci, Med Stat Team, Aberdeen, Scotland.4 aut
7001 a Hyland, Michael E.u School of Psychology, Plymouth University, Plymouth, UK,Univ Plymouth, Sch Psychol, Plymouth PL4 8AA, Devon, England.4 aut
7001 a Ställberg, Björnu Uppsala universitet,Allmänmedicin och preventivmedicin4 aut0 (Swepub:uu)bjsta623
7001 a Lisspers, Karinu Uppsala universitet,Allmänmedicin och preventivmedicin4 aut0 (Swepub:uu)kalis120
7001 a Sundh, Josefin,d 1972-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Respiratory Medicine, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden,Univ Orebro, Sch Hlth & Med Sci, Dept Resp Med, Orebro Univ Hosp, SE-70182 Orebro, Sweden.4 aut0 (Swepub:oru)jnsh
7001 a van der Molen, Thysu University Medical Center Groningen, Department of General Practice, University of Groningen, Groningen, The Netherlands,Univ Groningen, Univ Med Ctr Groningen, Dept Gen Practice, Groningen, Netherlands.4 aut
7001 a Tsiligianni, Ioannau University Medical Center Groningen, Department of General Practice, University of Groningen, Groningen, The Netherlands,Univ Groningen, Univ Med Ctr Groningen, Dept Gen Practice, Groningen, Netherlands.4 aut
7102 a Clinical Trials and Population Studies, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UKb Univ Plymouth, Peninsula Sch Med, Clin Trials & Populat Studies, ITTC Bldg N14,Plymouth Sci Pk, Plymouth PL4 8AA, Devon, England.;Univ Plymouth, Peninsula Sch Dent, Clin Trials & Populat Studies, ITTC Bldg N14,Plymouth Sci Pk, Plymouth PL4 8AA, Devon, England.4 org
7730 t npj Primary Care Respiratory Medicined London, United Kingdom : Nature Publishing Groupg 26q 26x 2055-1010
8564 u https://doi.org/10.1038/npjpcrm.2016.10y Fulltext
8564 u https://doi.org/10.1038/npjpcrm.2016.10
8564 u https://uu.diva-portal.org/smash/get/diva2:941661/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-49813
8564 8u https://doi.org/10.1038/npjpcrm.2016.10
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297373

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