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Sökning: onr:"swepub:oai:DiVA.org:oru-54409" > Novel Chlorinated P...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008993naa a2200493 4500
001oai:DiVA.org:oru-54409
003SwePub
008170110s2017 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-544092 URI
0247 a https://doi.org/10.1021/acs.est.6b045902 DOI
040 a (SwePub)oru
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Pan, Yitaou Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. China4 aut
2451 0a Novel Chlorinated Polyfluorinated Ether Sulfonates and Legacy Per-/Polyfluoroalkyl Substances :b Placental Transfer and Relationship with Serum Albumin and Glomerular Filtration Rate
264 c 2016-12-22
264 1a Dordrecht, Neteherlands :b Springer Netherlands,c 2017
338 a print2 rdacarrier
500 a Funding Agency:Strategic Priority Research Program of the Chinese Academy of Sciences XDB14040202National Natural Science Foundation of China 31320103915 21437002 81372959 81402649Fundamental Research Funds for the Central Universities, HUST 2016YXZD043
520 a Per- and polyfluoroalkyl substances (PFASs) may cross the placental barrier and lead to fetal exposure. However, little is known about the factors that influence maternal-fetal transfer of these chemicals. PFAS concentrations were analyzed in 100 paired samples of human maternal sera collected in each trimester and cord sera at delivery; these samples were collected in Wuhan, China, 2014. Linear regression was used to estimate associations of transfer efficiencies with factors. Chlorinated polyfluorinated ether sulfonates (Cl-PFAESs, 6:2 and 8:2) were frequently detected (>99%) in maternal and cord sera. A significant decline in PFAS levels during the three trimesters was observed. A U-shape trend for transfer efficiency with increasing chain length was observed for both carboxylates and sulfonates. Higher transfer efficiencies of PFASs were associated with advancing maternal age, higher education, and lower glomerular filtration rate (GFR). Cord serum albumin was a positive factors for higher transfer efficiency (increased 1.1-4.1% per 1g/L albumin), whereas maternal serum albumin tended to reduce transfer efficiency (decreased 2.4-4.3% per 1g/L albumin). Our results suggest that exposure to Cl-PFAESs may be widespread in China. The transfer efficiencies among different PFASs were structure-dependent. Physiological factors (e.g., GFR and serum albumin) were observed for the first time to play critical roles in PFAS placental transfer.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng
7001 a Zhu, Yingshuangu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Zheng, Tongzhangu Department of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States4 aut
7001 a Cui, Qianqianu Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. China4 aut
7001 a Buka, Stephen L.u Department of Epidemiology, School of Public Health, Brown University, Providence RI, United States4 aut
7001 a Zhang, Binu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; Women and Children Medical and Healthcare Center of Wuhan, Wuhan, P. R. China4 aut
7001 a Guo, Yongu Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, P. R. China4 aut
7001 a Xia, Weiu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Yeung, Leo W. Y.,d 1981-u Örebro universitet,Institutionen för naturvetenskap och teknik,Man-Technology-Environment Research Centre (MTM)4 aut0 (Swepub:oru)lyg
7001 a Li, Yuanyuanu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Zhou, Aifenu Women and Children Medical and Healthcare Center of Wuhan, Wuhan, P. R. China4 aut
7001 a Qiu, Linu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; Women and Children Medical and Healthcare Center of Wuhan, Wuhan, P. R. China4 aut
7001 a Liu, Hongxiuu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; Women and Children Medical and Healthcare Center of Wuhan, P. R. China4 aut
7001 a Jiang, Minminu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Wu, Chuanshau Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Xu, Shunqingu Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 aut
7001 a Dai, Jiayinu Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. China4 aut
7102 a Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, P. R. Chinab Key Laboratory of Environment and Health (HUST), Ministry of Education & Ministry of Environmental Protection, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China; State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China4 org
7730 t Environmental Science and Technologyd Dordrecht, Neteherlands : Springer Netherlandsg 51:1, s. 634-644q 51:1<634-644x 0013-936Xx 1520-5851
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-54409
8564 8u https://doi.org/10.1021/acs.est.6b04590

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