Sökning: onr:"swepub:oai:DiVA.org:oru-54620" >
A Genetically Infor...
A Genetically Informed Study of the Associations Between Maternal Age at Childbearing and Adverse Perinatal Outcomes
-
- Sujan, Ayesha C. (författare)
- Department of Psychological and Brain Sciences, Indiana University, Bloomington, USA
-
- Rickert, Martin E. (författare)
- Department of Psychological and Brain Sciences, Indiana University, Bloomington, USA
-
- Class, Quetzal A. (författare)
- Karolinska Institutet
-
visa fler...
-
- Coyne, Claire A. (författare)
- Ann and Robert H. Lurie Children’s Hospital, Chicago, USA
-
- Lichtenstein, Paul (författare)
- Karolinska Institutet
-
- Almqvist, Catarina (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Stockholm, Sweden
-
- Larsson, Henrik, 1975- (författare)
- Karolinska Institutet
-
- Sjölander, Arvid (författare)
- Karolinska Institutet
-
- Lahey, Benjamin B. (författare)
- Department of Public Health Sciences, University of Chicago, Chicago, USA
-
- van Hulle, Carol (författare)
- Waisman Center, University of Wisconsin, Madison, USA
-
- Waldman, Irwin (författare)
- Department of Psychology, Emory University, Atlanta, USA
-
- Öberg, A. Sara (författare)
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, USA
-
- D'Onofrio, Brian M. (författare)
- Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
-
-
visa fler...
-
-
visa färre...
- ISSN 0001-8244
- 2015-09-24
- 2016
- Engelska.
-
Ingår i: Behavior Genetics. - New York, USA : Springer. - 0001-8244 .- 1573-3297. ; 46:3, s. 431-456
- Relaterad länk:
-
http://openarchive.k...
-
visa fler...
-
http://hdl.handle.ne... (primary) (Object in context) (free)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://hdl.handle.ne...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- We examined associations of maternal age at childbearing (MAC) with gestational age and fetal growth (i.e., birth weight adjusting for gestational age), using two genetically informed designs (cousin and sibling comparisons) and data from two cohorts, a population-based Swedish sample and a nationally representative United States sample. We also conducted sensitivity analyses to test limitations of the designs. The findings were consistent across samples and suggested that, associations observed in the population between younger MAC and shorter gestational age were confounded by shared familial factors; however, associations of advanced MAC with shorter gestational age remained robust after accounting for shared familial factors. In contrast to the gestational age findings, neither early nor advanced MAC was associated with lower fetal growth after accounting for shared familial factors. Given certain assumptions, these findings provide support for a causal association between advanced MAC and shorter gestational age. The results also suggest that there are not causal associations between early MAC and shorter gestational age, between early MAC and lower fetal growth, and between advanced MAC and lower fetal growth.
Ämnesord
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- Gestational age
- birth weight
- fetal growth
- maternal age at childbearing
- genetically informed designs
- quasi-experiments
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Sujan, Ayesha C.
-
Rickert, Martin ...
-
Class, Quetzal A ...
-
Coyne, Claire A.
-
Lichtenstein, Pa ...
-
Almqvist, Catari ...
-
visa fler...
-
Larsson, Henrik, ...
-
Sjölander, Arvid
-
Lahey, Benjamin ...
-
van Hulle, Carol
-
Waldman, Irwin
-
Öberg, A. Sara
-
D'Onofrio, Brian ...
-
visa färre...
- Om ämnet
-
- NATURVETENSKAP
-
NATURVETENSKAP
-
och Biologi
-
och Genetik
-
- SAMHÄLLSVETENSKAP
-
SAMHÄLLSVETENSKA ...
-
och Psykologi
- Artiklar i publikationen
-
Behavior Genetic ...
- Av lärosätet
-
Örebro universitet
-
Karolinska Institutet