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A longitudinal stud...
A longitudinal study of adolescent psychotic experiences and later development of substance use disorder and suicidal behavior
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- Martin, Cederlöf, 1980- (författare)
- Karolinska Institutet
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- Kuja-Halkola, Ralf (författare)
- Karolinska Institutet
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- Larsson, Henrik, 1975- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
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- Sjölander, Arvid (författare)
- Karolinska Institutet
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- Östberg, Per (författare)
- Karolinska Institutet
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- Lundström, Sebastian (författare)
- Gothenburg University,Göteborgs universitet,Centrum för etik, juridik och mental hälsa,Gillbergcentrum,Centre for Ethics, Law, and Mental Health,Gillberg Neuropsychiatry Centre
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- Kelleher, Ian (författare)
- Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
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- Lichtenstein, Paul (författare)
- Karolinska Institutet
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(creator_code:org_t)
- Amsterdam, Netherlands : Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Schizophrenia Research. - Amsterdam, Netherlands : Elsevier. - 0920-9964 .- 1573-2509. ; 181, s. 13-16
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- Introduction: Psychotic experiences are associated with later substance use disorder and suicidal behavior, but individual psychotic experiences have not been examined in a longitudinal data set. Also, the potential dose-response relationship between these phenomena remains unknown.Method: Cohort study including 9242 adolescents who participated in The Child and Adolescent Twin Study in Sweden (CATSS). At ages 15 and/or 18, seven psychotic experiences (auditory and visual hallucinations, and five delusions) were assessed via questionnaires. Outcomes at follow-up were physician-assigned diagnoses of substance use disorder and suicide attempts ascertained from the Swedish Patient Register. Associations were estimated with Cox regressions and expressed as hazard ratios.Results: All psychotic experiences were associated with later substance use disorder and/or suicide attempts, with hazard ratios ranging from 1.6 to 3.0. A dose-response relationship was observed between psychotic experiences and later substance use disorder, and suicide attempt.Discussion: Auditory and visual hallucinations as well as delusions in adolescence are associated with later development of substance use disorder and suicide attempt, and there is a dose-response relationship between the load of psychotic experiences and these adverse outcomes. Clinicians should assess subclinical hallucinations as well as delusions in psychiatric evaluations of adolescents.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Beroendelära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Substance Abuse (hsv//eng)
Nyckelord
- Psychotic experiences
- substance use disorder
- suicide attempt
- epidemiology
- Psychiatry
- Psykiatri
- Epidemiology; Psychotic experiences; Substance use disorder; Suicide attempt
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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