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Disentangling Heter...
Disentangling Heterogeneity of Childhood Disruptive Behavior Problems Into Dimensions and Subgroups
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- Bolhuis, Koen (författare)
- Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
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- Lubke, Gitta H. (författare)
- University of Notre Dame, Notre Dame IN, United States; Vrije Universiteit, Amsterdam, Netherlands
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- van der Ende, Jan (författare)
- Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
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- Bartels, Meike (författare)
- Vrije Universiteit, Amsterdam, Netherlands
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- van Beijsterveldt, Catharina E. M. (författare)
- Vrije Universiteit, Amsterdam, Netherlands
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- Lichtenstein, Paul (författare)
- Karolinska Institutet
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- Larsson, Henrik, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Karolinska Institutet, Stockholm, Sweden
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- Jaddoe, Vincent W. V. (författare)
- Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
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- Kushner, Steven A. (författare)
- Erasmus Medical Center, Rotterdam, Netherlands
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- Verhulst, Frank C. (författare)
- Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
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- Boomsma, Dorret I. (författare)
- Vrije Universiteit, Amsterdam, Netherlands
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- Tiemeier, Henning (författare)
- Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
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(creator_code:org_t)
- Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Journal of the American Academy of Child and Adolescent Psychiatry. - : Elsevier. - 0890-8567 .- 1527-5418. ; 56:8, s. 678-686
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective: Irritable and oppositional behaviors are increasingly considered as distinct dimensions of oppositional defiant disorder. However, few studies have explored this multidimensionality across the broader spectrum of disruptive behavior problems (DBPs). This study examined the presence of dimensions and distinct subgroups of childhood DBPs, and the cross-sectional and longitudinal associations between these dimensions.Method: Using factor mixture models (FMMs), the presence of dimensions and subgroups of DBPs was assessed in the Generation R Study at ages 6 (n = 6,209) and 10 (n = 4,724) years. Replications were performed in two population-based cohorts (Netherlands Twin Registry, n = 4,402, and Swedish Twin Study of Child and Adolescent Development, n = 1,089) and a clinical sample (n = 1,933). We used cross-lagged modeling in the Generation R Study to assess cross-sectional and longitudinal associations between dimensions. DBPs were assessed using mother-reported responses to the Child Behavior Checklist.Results: Empirically obtained dimensions of DBPs were oppositional behavior (age 6 years), disobedient behavior, rule-breaking behavior (age 10 years), physical aggression, and irritability (both ages). FMMs suggested that one-class solutions had the best model fit for all dimensions in all three population-based cohorts. Similar results were obtained in the clinical sample. All three dimensions, including irritability, predicted subsequent physical aggression (range, 0.08-0.16).Conclusion: This study showed that childhood DBPs should be regarded as a multidimensional phenotype rather than comprising distinct subgroups. Incorporating multidimensionality will improve diagnostic accuracy and refine treatment. Future studies need to address the biological validity of the DBP dimensions observed in this study; herein lies an important opportunity for neuro-imaging and genetic measures.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- disruptive behavior disorder
- classification
- DSM-5
- irritable mood
- factor mixture model
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- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Bolhuis, Koen
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Lubke, Gitta H.
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van der Ende, Ja ...
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Bartels, Meike
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van Beijsterveld ...
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Lichtenstein, Pa ...
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visa fler...
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Larsson, Henrik, ...
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Jaddoe, Vincent ...
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Kushner, Steven ...
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Verhulst, Frank ...
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Boomsma, Dorret ...
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Tiemeier, Hennin ...
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- Om ämnet
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- SAMHÄLLSVETENSKAP
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SAMHÄLLSVETENSKA ...
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och Psykologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Pediatrik
- Artiklar i publikationen
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Journal of the A ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet