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Satellite cells and...
Satellite cells and myonuclei in young and elderly women and men
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- Kadi, Fawzi (författare)
- Örebro universitet,Hälsoakademin,RISPA,Department of Physical Education and Health, Örebro University, Örebro, Sweden
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- Charifi, Nadia (författare)
- Laboratoire de Physiologie, Grp. Interet Pub. Exercice-Sport-S., Université Saint-Etienne, Saint-Etienne, France
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- Denis, Christian (författare)
- Laboratoire de Physiologie, Grp. Interet Pub. Exercice-Sport-S., Université Saint-Etienne, Saint-Etienne, France
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- Lexell, Jan (författare)
- Luleå tekniska universitet,Lund University,Lunds universitet,Rehabiliteringsmedicin,Forskargrupper vid Lunds universitet,Rehabilitation medicine,Lund University Research Groups,Department of Rehabilitation, Lund University Hospital, Lund, Sweden;Department of Community Medicine, Division of Geriatrics, Lund University, Malmö, Sweden
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(creator_code:org_t)
- 2003
- 2004
- Engelska.
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Ingår i: Muscle and Nerve. - : Wiley. - 0148-639X .- 1097-4598. ; 29:1, s. 120-127
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The overall aim of this study was to assess the effects of aging on the satellite cell population. Muscle biopsies were taken from the tibialis anterior muscle of healthy, moderately active young (age range, 20-32 years; n = 31) and elderly (age range, 70-83 years; n = 27) women and men with comparable physical activity pattern. Satellite cells and myonuclei were visualized using a monoclonal antibody against neural cell adhesion molecule and counterstained with Mayer's hematoxylin. An average of 211 (range, 192-241) muscle fibers were examined for each individual. Compared with the young women and men, the elderly subjects had a significantly lower (P < 0.011) number of satellite cells per muscle fiber but a significantly higher (P < 0.004) number of myonuclei per muscle fiber. The number of satellite cells relative to the total number of nuclei [satellite cells/(myonuclei + satellite cells)] was significantly lower in the elderly than in the young women and men. These results imply that a reduction in the satellite cell population occurs as a result of increasing age in healthy men and women.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- SAMHÄLLSVETENSKAP -- Annan samhällsvetenskap -- Tvärvetenskapliga studier inom samhällsvetenskap (hsv//swe)
- SOCIAL SCIENCES -- Other Social Sciences -- Social Sciences Interdisciplinary (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- MEDICINE
- MEDICIN
- Physiology
- Fysiologi
- INTERDISCIPLINARY RESEARCH AREAS
- TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN
- Sports
- Idrott
- Sports Science
- Idrottsvetenskap
- sex characteristics
- satellite cells
- myonuclei
- aging
- muscle fibers
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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