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Sökning: onr:"swepub:oai:DiVA.org:oru-68142" > Risk of Fractures i...

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FältnamnIndikatorerMetadata
00005149naa a2200457 4500
001oai:DiVA.org:oru-68142
003SwePub
008180726s2018 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-360434
009oai:prod.swepub.kib.ki.se:138630785
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-681422 URI
0247 a https://doi.org/10.1016/j.jpeds.2018.02.0702 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3604342 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1386307852 URI
040 a (SwePub)orud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Canova, Cristinau Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italy,Univ Padua, Dept Cardiol Thorac & Vasc Sci, Padua, Italy4 aut
2451 0a Risk of Fractures in Youths with Celiac Disease :b A Population-Based Study
264 1b Elsevier,c 2018
338 a print2 rdacarrier
500 a Funding Agency:University of Padua  F.S. 4.18.01.05
520 a Objective: To assess the risk of any fracture requiring hospital care in a cohort of individuals with celiac disease diagnosed in childhood/adolescence compared with reference individuals matched by age and sex.Study design: Our study cohort consisted of 213 635 people born and residing in Friuli-Venezia Giulia Region, Italy, in 1989-2011. We selected, through pathology reports, hospital discharge records, or co-payment exemptions, 1233 individuals with celiac disease (aged 0-17 years at diagnosis) and compared them with 6167 reference individuals matched by sex and year of birth. Fractures were identified through hospital discharge records. We calculated hazard ratios (HRs) for any fracture after celiac disease diagnosis (or index date for reference individuals) with Cox regression and ORs for any fracture before celiac disease diagnosis with conditional logistic regression.Results: During the follow-up period (maximum 23 years), 22 individuals with celiac disease (9394 person-years) and 128 reference individuals (47 308 person-years) experienced a fracture. giving an overall HR of 0.87 (95% CI 0.55-1.37). The risk was not modified by sex, age at diagnosis, or calendar period of diagnosis. We obtained similar HRs when excluding fractures occurring after the age of 18 years and adjusting for maternal education or vitamin D supplementation. The odds of previous fracture also did not differ between subjects with celiac disease and reference individuals (22 and 96 cases, respectively: OR 1.15: 95% CI 0.72-1.84).Conclusions: We did not find any evidence of an increased risk of fractures during childhood and youth among patients with celiac disease.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
7001 a Pitter, Gisellau Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italy,Univ Padua, Dept Cardiol Thorac & Vasc Sci, Padua, Italy4 aut
7001 a Zanier, Lorisu Epidemiological Service, Health Directorate, Friuli Venezia-Giulia Region, Udine, Italy,Hlth Directorate, Epidemiol Serv, Udine, Italy4 aut
7001 a Simonato, Lorenzou Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italy,Univ Padua, Dept Cardiol Thorac & Vasc Sci, Padua, Italy4 aut
7001 a Michaëlsson, Karl,d 1959-u Uppsala universitet,Ortopedi4 aut0 (Swepub:uu)karlmich
7001 a Ludvigsson, Jonas F.,d 1969-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Pediatrics, Örebro University Hospital, Örebro University, Örebro, Sweden; Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom; Department of Medicine, Columbia University College of Physicians and Surgeons, New York NY, USA4 aut0 (Swepub:oru)jsln
7001 a Ludvigsson, Jonas E.u Karolinska Institutet4 aut
7102 a Department of Cardiological, Thoracic and Vascular Sciences, University of Padua, Padua, Italyb Univ Padua, Dept Cardiol Thorac & Vasc Sci, Padua, Italy4 org
7730 t The Journal of Pediatricsd : Elsevierg 198, s. 117-120q 198<117-120x 0022-3476x 1097-6833
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-68142
8564 8u https://doi.org/10.1016/j.jpeds.2018.02.070
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-360434
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:138630785

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