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Development of an I...
Development of an ICU discharge instrument predicting psychological morbidity : a multinational study
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- Milton, A. (författare)
- Karolinska Institutet
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- Schandl, A. (författare)
- Karolinska Institutet
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- Soliman, I. W. (författare)
- Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands,Univ Utrecht, Univ Med Ctr Utrecht, Dept Intens Care Med, Utrecht, Netherlands
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- Meijers, K. (författare)
- Department of Anaesthesiology and Intensive Care, Södersjukhuset, Stockholm, Sweden,Soder Sjukhuset, Dept Anaesthesiol & Intens Care, Stockholm, Sweden
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- van den Boogaard, M. (författare)
- Department of Intensive Care Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands,Radboud Univ Nijmegen, Med Ctr, Dept Intens Care Med, Nijmegen, Netherlands
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- Larsson, Ing-Marie, 1963- (författare)
- Uppsala universitet,Anestesiologi och intensivvård
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- Brorsson, Camilla (författare)
- Umeå universitet,Anestesiologi och intensivvård,Umea Univ, Dept Surg & Perioperat Sci, Umea, Sweden
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- Östberg, U. (författare)
- Department of Anaesthesiology and Intensive Care, Östersund Hospital, Östersund, Sweden,Ostersund Hosp, Dept Anaesthesiol & Intens Care, Ostersund, Sweden
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- Oxenbøll-Collet, M. (författare)
- Department of Intensive Care, Rigshospitalet Copenhagen, Copenhagen, Denmark,Rigshosp Copenhagen, Dept Intens Care, Copenhagen, Denmark
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- Savilampi, Johanna, 1977- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Anaesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden,Orebro Univ Hosp, Dept Anaesthesiol & Intens Care, Orebro, Sweden
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- Paskins, S. (författare)
- Department of Intensive Care, Odense University Hospital, Odense, Denmark,Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden,Odense Univ Hosp, Dept Intens Care, Odense, Denmark,Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden
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- Bottai, M. (författare)
- Karolinska Institutet
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- Sackey, P. V. (författare)
- Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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(creator_code:org_t)
- 2018-11-22
- 2018
- Engelska.
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Ingår i: Intensive Care Medicine. - : Springer. - 0342-4642 .- 1432-1238. ; 44:12, s. 2038-2047
- Relaterad länk:
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https://doi.org/10.1...
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https://link.springe...
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https://umu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Purpose: To develop an instrument for use at ICU discharge for prediction of psychological problems in ICU survivors.Methods: Multinational, prospective cohort study in ten general ICUs in secondary and tertiary care hospitals in Sweden, Denmark and the Netherlands. Adult patients with an ICU stay12h were eligible for inclusion. Patients in need of neurointensive care, with documented cognitive impairment, unable to communicate in the local language, without a home address or with more than one limitation of therapy were excluded. Primary outcome was psychological morbidity 3months after ICU discharge, defined as Hospital Anxiety and Depression Scale (HADS) subscale score11 or Post-traumatic Stress Symptoms Checklist-14 (PTSS-14) part B score>45.Results: A total of 572 patients were included and 78% of patients alive at follow-up responded to questionnaires. Twenty percent were classified as having psychological problems post-ICU. Of 18 potential risk factors, four were included in the final prediction model after multivariable logistic regression analysis: symptoms of depression [odds ratio (OR) 1.29, 95% confidence interval (CI) 1.10-1.50], traumatic memories (OR 1.44, 95% CI 1.13-1.82), lack of social support (OR 3.28, 95% CI 1.47-7.32) and age (age-dependent OR, peak risk at age 49-65years). The area under the receiver operating characteristics curve (AUC) for the instrument was 0.76 (95% CI 0.70-0.81).Conclusions: We developed an instrument to predict individual patients' risk for psychological problems 3months post-ICU, http://www.imm.ki.se/biostatistics/calculators/psychmorb/. The instrument can be used for triage of patients for psychological ICU follow-up.Trial registration: The study was registered at clinicaltrials.gov, NCT02679157.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- Intensive care
- PICS
- Follow-up
- Depression
- Post-traumatic stress
- Anxiety
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Milton, A.
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Schandl, A.
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Soliman, I. W.
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Meijers, K.
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van den Boogaard ...
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Larsson, Ing-Mar ...
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visa fler...
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Brorsson, Camill ...
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Östberg, U.
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Oxenbøll-Collet, ...
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Savilampi, Johan ...
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Paskins, S.
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Bottai, M.
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Sackey, P. V.
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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Intensive Care M ...
- Av lärosätet
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Örebro universitet
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Umeå universitet
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Uppsala universitet
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Karolinska Institutet