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Differences of FENO...
Differences of FENO in adult general populations of Nordic regions
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- Lassmann-Klee, Paul (författare)
- Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
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- Brumpton, Ben (författare)
- Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology and Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
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- Henriksen, Anne Hildur (författare)
- Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
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- Larsson, Matz, 1955- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,University of Lund, Lund, Sweden
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- Sundblad, Britt-Marie (författare)
- Karolinska Institute, Solna, Sweden
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- Polluste, Jaak (författare)
- The National Institute for Health Development, Tallinn, Estonia
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- Lindqvist, Ari (författare)
- Clinical Research Unit of Pulmonary Diseases, Helsinki University Hospital, Helsinki, Finland
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- Hedman, Linnea, 1979- (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Backman, Helena (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Rönmark, Eva (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Langhammer, Arnulf (författare)
- HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway
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- Piirilä, Päivi (författare)
- Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
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- Sovijärvi, Anssi R. A. (författare)
- Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
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Unit of Clinical Physiology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology and Clinic of Thoracic and Occupational Medicine, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway (creator_code:org_t)
- European Respiratory Society, 2019
- 2019
- Engelska.
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Ingår i: European Respiratory Journal. - : European Respiratory Society. - 0903-1936 .- 1399-3003. ; 54:Suppl. 63
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Eventual differences of expiratory nitric oxide (FENO) levels in general populations of Nordic countries may reflect differences in eosinophilic inflammation at population level.Aim: To study the differences in FENO of Nordic regions and their epidemiological associations.Methods: From 1997 to 2003 we measured FENO (ppb) and conducted skin prick-tests for a random sample of adults (n=1498), aged 20-60 years from Finland (Helsinki), Sweden (Stockholm and Örebro) and Estonia (Narva and Saaremaa). We compared differences between regions by estimating odds ratios (OR) and 95% confidence intervals (CIs) for high FENO (>25 ppb) using logistic regression adjusted for gender, smoking and allergy. Finally, we estimated crude ORs and 95% CIs for high FENO and for asthma, rhinitis, current asthma symptoms and asthma medication.Results: The mean and standard deviation (SD) for FENO was 19(14) in Finland, 18(12) in Sweden and 16(15) in Estonia (p<0.001). Estonia had a lower mean FENO than other countries, with no differences between Finland and Sweden. Compared to Helsinki, the adjusted OR (95%CI) for high FENO was 0.42(0.21-0.81) in Stockholm, 0.65(0.43-0.98) in Örebro, 0.53(0.32-0.84) in Narva and 0.45(0.28-0.71) in Saaremaa. In Estonia, high FENO was associated with asthma, allergy, rhinitis, current asthma, and asthma medication; in Finland with rhinitis and use of short acting β-agonist; in Sweden with asthma and asthma medication. Smoking was associated with low FENO. Mean FENO in asthmatics was 24(19) in Finland, 20(12) in Sweden, and 43(49) in Estonia (p=0.07).Conclusions: We observed a higher mean FENO in Finland and Sweden compared to Estonia, and found no overall differences of FENO levels in asthmatics.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
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Lassmann-Klee, P ...
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Brumpton, Ben
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Henriksen, Anne ...
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Larsson, Matz, 1 ...
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Sundblad, Britt- ...
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Polluste, Jaak
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Lindqvist, Ari
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Hedman, Linnea, ...
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Backman, Helena
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Rönmark, Eva
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Langhammer, Arnu ...
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Piirilä, Päivi
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Sovijärvi, Anssi ...
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Örebro universitet
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Umeå universitet
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