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Minimizing contrast...
Minimizing contrast media dose in CT pulmonary angiography with high-pitch technique
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- Alobeidi, Hanan (författare)
- Department of Radiology, Örebro university Hospital, Region Örebro län, Örebro, Sweden
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- Alshamari, Muhammed, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Radiology
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- Widell, Jonas (författare)
- Department of Radiology, Örebro university Hospital, Region Örebro län, Örebro, Sweden
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- Eriksson, Tomas (författare)
- Department of Radiology, Örebro university Hospital, Region Örebro län, Örebro, Sweden
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- Lidén, Mats, 1976- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Radiology
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(creator_code:org_t)
- John Wiley & Sons, 2020
- 2020
- Engelska.
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Ingår i: British Journal of Radiology. - : John Wiley & Sons. - 0007-1285 .- 1748-880X. ; 93:1111
- Relaterad länk:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: To perform CT pulmonary angiography (CTPA) using a minimal amount of iodinated contrast media.METHODS: 47 patients (25 females) with mean age 69 years (range 41-82 years) referred for contrast-enhanced chest CT were prospectively included in this Phase IV clinical drug trial. All participants underwent a study specific CTPA in addition to the chest CT. The participants received 80 mg I/kg body weight Iohexol contrast media using a preparatory saline bolus, a dual flow contrast/saline bolus and a saline flush, and a scanner protocol with 80 kVp dual source high-pitch mode. Three readers independently assessed the image quality on the 3-point scale non-diagnostic, adequate or good-excellent image quality. Additionally, the pulmonary arterial contrast opacification was measured.RESULTS: On average, the patients received 16.8 ml Iohexol 350 mg I/mL (range 12-20 ml). Mean patient weight was 71 kg (range 50-85 kg). Identically for all readers, pulmonary embolism (PE) was detected in 1/47 participants. The median number of examinations visually scored concerning pulmonary embolism as good-excellent was 47/47 (range 44-47); adequate 0/47 (0-3) and non-diagnostic 0/47 (range 0-0). The proportion adequate or better examinations was for all readers 47/47, 100% [95% confidence interval 92-100%]. The mean attenuation ± standard deviation in the pulmonary trunk was 325 ± 72 Hounsfield unit (range 165-531 Hounsfield unit).CONCLUSIONS: Diagnostic CTPA with 17 ml contrast media is possible in non-obese patients using low kVp, high pitch and carefully designed contrast media administration.ADVANCES IN KNOWLEDGE: By combining several procedures in a CTPA protocol, the contrast media dose can be minimized.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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