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The Atlas of Inflam...
The Atlas of Inflammation Resolution (AIR)
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- Serhan, Charles N. (författare)
- Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
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- Gupta, Shailendra K. (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Perretti, Mauro (författare)
- The William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK
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- Godson, Catherine (författare)
- Diabetes Complications Research Centre, Conway Institute & School of Medicine, University College Dublin, Belfield, Dublin, Ireland
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- Brennan, Eoin (författare)
- Diabetes Complications Research Centre, Conway Institute & School of Medicine, University College Dublin, Belfield, Dublin, Ireland
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- Li, Yongsheng (författare)
- Department of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, 400030, China
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- Soehnlein, Oliver (författare)
- Karolinska Institutet
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- Shimizu, Takao (författare)
- Department of Lipidomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo, Japan
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- Werz, Oliver (författare)
- Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Jena, Germany
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- Chiurchiù, Valerio (författare)
- Institute of Translational Pharmacology, National Research Council, Rome, Italy; Laboratory of Resolution of Neuroinflammation, IRCCS Santa Lucia Foundation, Rome, Italy
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- Azzi, Angelo (författare)
- School of Graduate Biomedical Pharmacology and Drug Development Program at Tufts University, Boston, MA, USA
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- Dubourdeau, Marc (författare)
- Ambiotis, Canal Biotech, Toulouse, France
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- Gupta, Suchi Smita (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Schopohl, Patrick (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Hoch, Matti (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Gjorgevikj, Dragana (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Khan, Faiz M. (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Brauer, David (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany
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- Tripathi, Anurag (författare)
- CSIR - Indian Institute of Toxicology Research, Lucknow, India
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- Cesnulevicius, Konstantin (författare)
- Department of Medical Affairs & Research, Heel GmbH, Baden-Baden, Germany
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- Lescheid, David (författare)
- Department of Medical Affairs & Research, Heel GmbH, Baden-Baden, Germany
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- Schultz, Myron (författare)
- Department of Medical Affairs & Research, Heel GmbH, Baden-Baden, Germany
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- Särndahl, Eva, 1963- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,IRiSC - Inflammatory Response and Infection Susceptibility Centre
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- Repsilber, Dirk, 1971- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper
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- Kruse, Robert, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Clinical Research Laboratory,IRiSC - Inflammatory Response and Infection Susceptibility Centre
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- Sala, Angelo (författare)
- Department of Pharmaceutical Sciences, University of Milan, Milano, and IRIB, C.N.R, Palermo, Italy
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- Haeggström, Jesper Z. (författare)
- Karolinska Institutet
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- Levy, Bruce D. (författare)
- Brigham and Women's Hospital, Department of Medicine, Pulmonary and Critical Care Medicine and Harvard Medical School, Boston, MA, USA
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- Filep, János G. (författare)
- Department of Pathology and Cell Biology, University of Montreal, Research Center, Maisonneuve-Rosemont Hospital, Montreal, Canada
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- Wolkenhauer, Olaf (författare)
- Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany; Stellenbosch Institute for Advanced Study (STIAS), Wallenberg Research Centre at Stellenbosch University, Stellenbosch, South Africa
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(creator_code:org_t)
- Elsevier, 2020
- 2020
- Engelska.
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Ingår i: Molecular Aspects of Medicine. - : Elsevier. - 0098-2997 .- 1872-9452. ; 74
- Relaterad länk:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Acute inflammation is a protective reaction by the immune system in response to invading pathogens or tissue damage. Ideally, the response should be localized, self-limited, and returning to homeostasis. If not resolved, acute inflammation can result in organ pathologies leading to chronic inflammatory phenotypes. Acute inflammation and inflammation resolution are complex coordinated processes, involving a number of cell types, interacting in space and time. The biomolecular complexity and the fact that several biomedical fields are involved, make a multi- and interdisciplinary approach necessary. The Atlas of Inflammation Resolution (AIR) is a web-based resource capturing an essential part of the state-of-the-art in acute inflammation and inflammation resolution research. The AIR provides an interface for users to search thousands of interactions, arranged in inter-connected multi-layers of process diagrams, covering a wide range of clinically relevant phenotypes. By mapping experimental data onto the AIR, it can be used to elucidate drug action as well as molecular mechanisms underlying different disease phenotypes. For the visualization and exploration of information, the AIR uses the Minerva platform, which is a well-established tool for the presentation of disease maps. The molecular details of the AIR are encoded using international standards. The AIR was created as a freely accessible resource, supporting research and education in the fields of acute inflammation and inflammation resolution. The AIR connects research communities, facilitates clinical decision making, and supports research scientists in the formulation and validation of hypotheses. The AIR is accessible through https://air.bio.informatik.uni-rostock.de.
Ämnesord
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
Nyckelord
- Acute inflammation
- Disease map
- Inflammation resolution
- Inflammatory mediators
- Molecular interaction map
- Molecular switches
- Pro-resolving mediators
- Systems biology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Serhan, Charles ...
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Gupta, Shailendr ...
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Perretti, Mauro
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Godson, Catherin ...
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Brennan, Eoin
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Li, Yongsheng
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visa fler...
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Soehnlein, Olive ...
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Shimizu, Takao
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Werz, Oliver
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Chiurchiù, Valer ...
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Azzi, Angelo
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Dubourdeau, Marc
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Gupta, Suchi Smi ...
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Schopohl, Patric ...
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Hoch, Matti
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Gjorgevikj, Drag ...
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Khan, Faiz M.
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Brauer, David
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Tripathi, Anurag
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Cesnulevicius, K ...
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Lescheid, David
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Schultz, Myron
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Särndahl, Eva, 1 ...
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Repsilber, Dirk, ...
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Kruse, Robert, 1 ...
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Sala, Angelo
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Haeggström, Jesp ...
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Levy, Bruce D.
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Filep, János G.
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Wolkenhauer, Ola ...
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- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Data och informa ...
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och Datavetenskap
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinsk biotek ...
- Artiklar i publikationen
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Molecular Aspect ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet