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Cost-effectiveness ...
Cost-effectiveness of an indicated preventive intervention for depression in adolescents
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- Ssegonja, R. (författare)
- Child Health and Parenting, Uppsala University, Institute of Public Health and Caring Sciences, Uppsala, Sweden
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- Sampaio, F. (författare)
- Child Health and Parenting, Uppsala University, Institute of Public Health and Caring Sciences, Uppsala, Sweden
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- Alaie, I. (författare)
- Child and Adolescent Psychiatry, Uppsala University, Department of Neuroscience, Uppsala, Sweden
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- Philipson, Anna, 1978- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper
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- Hagberg, Lars, 1956- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,Region Örebro län
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- Murray, K. (författare)
- Toronto Health Economics and Technology Assessment, THETA collaborative, University of Toronto, Toronto, Canada
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- Sarkadi, A. (författare)
- Child Health and Parenting, Uppsala University, Institute of Public Health and Caring Sciences, Uppsala, Sweden; Murdoch Children’s Research Institute, Murdoch Children’s Research Institute, Melbourne, Australia
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- Langenskiöld, S. (författare)
- LIME, Department of Learning, Informatics, Management and Ethics, Karolinska Institute, Stockholm, Sweden; Cardiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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- Jonsson, U. (författare)
- Pediatric Neuropsychiatry Unit, Center of Neurodevelopmental Disorders at Karolinska Institutet, Stockholm, Sweden; Centre for Psychiatry Research, Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden
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- Feldman, I. (författare)
- Child Health and Parenting, Uppsala University, Institute of Public Health and Caring Sciences, Uppsala, Sweden
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(creator_code:org_t)
- 2020-09-30
- 2020
- Engelska.
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Ingår i: European Journal of Public Health. - : Oxford University Press. - 1101-1262 .- 1464-360X. ; 30:Suppl. 5, s. V914-V914
- Relaterad länk:
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Adolescent depression has negative health and economic outcomes in the short- and long-term. Indicated preventive interventions, in particular group based cognitive behavioural therapy (GB-CBT), are effective in preventing depression in adolescents with subsyndromal depression. However, little is known about the cost-effectiveness of these interventions.Methods: A Markov cohort model was used to conduct cost-effectiveness analyses comparing a GB-CBT indicated preventive intervention for depression, to a no-intervention option. Taking a time horizon of 5- and 10 years, incremental differences in societal costs and health benefits expressed as cases of depression prevented, and as quality adjusted life years (QALYs) gained were estimated. Through univariate and probabilistic sensitivity analyses, the robustness of the results was explored. Costs, presented in 2018 USD, and effects were discounted at a yearly rate of 3%.Results: The base-case analysis showed that GB-CBT indicated preventive intervention incurred lower costs, prevented more cases of depression and generated higher QALYs compared to the no-intervention option for both time horizons. Offering the intervention was even a cost saving strategy and demonstrated a probability of being cost-effective of over 95%. In the sensitivity analyses, these results were robust to the modelling assumptions.Limitations: The study considered a homogeneous cohort and assumed a constant annual decay rate of the relative treatment effect.Conclusions: GB-CBT indicated preventive interventions for depression in adolescence can generate good value for money compared to leaving adolescents with subsyndromal depression untreated.Key messages:Indicated preventive interventions for depression are cost-saving and can generate substantial health benefits.Indicated preventive interventions can be adopted as cost-effective preventive strategies for depression.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
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Ssegonja, R.
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Sampaio, F.
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Alaie, I.
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Philipson, Anna, ...
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Hagberg, Lars, 1 ...
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Murray, K.
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Sarkadi, A.
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Langenskiöld, S.
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Jonsson, U.
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Feldman, I.
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Örebro universitet