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Longitudinal Associations Between Symptoms of ADHD and BMI From Late Childhood to Early Adulthood

Kase, Bezawit E. (author)
Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
Rommelse, Nanda (author)
Department of Psychiatry, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, Netherlands
Chen, Qi (author)
Karolinska Institutet
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Li, Lin, 1989- (author)
Örebro universitet,Institutionen för medicinska vetenskaper
Andersson, Anneli, 1992- (author)
Örebro universitet,Institutionen för medicinska vetenskaper
Du Rietz, Ebba (author)
Karolinska Institutet
Vos, Melissa (author)
Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
Cortese, Samuele (author)
Center for Innovation in Mental Health, School of Psychology, Clinical and Experimental Sciences (CNS and Psychiatry), University of Southampton, Southampton, United Kingdom; Solent National Health Services Trust, Southampton, United Kingdom; Department of Child and Adolescent Psychiatry, Hassenfeld Children's Hospital at NYU Langone, New York, New York, USA; Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, United Kingdom
Larsson, Henrik, 1975- (author)
Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
Hartman, Catharina A (author)
Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
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 (creator_code:org_t)
2021-06-01
2021
English.
In: Pediatrics. - : American Academy of Pediatrics. - 0031-4005 .- 1098-4275. ; 147:6
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • BACKGROUND AND OBJECTIVES: Attention-deficit/hyperactivity disorder (ADHD) and obesity are 2 frequent conditions that co-occur, which has implications for the management of both conditions. We hypothesized that ADHD symptoms predict BMI and vice versa from late childhood (10-12 years) up to early adulthood (20-22 years).METHODS: Participants were adolescents in the Netherlands (n = 2773, 52.5% male, mean age = 11 years at baseline, 5 waves up to mean age 22) from the Tracking Adolescents' Individual Lives Survey cohort. We examined bidirectional relationship between ADHD symptoms (hyperactivity/impulsivity and inattention) and BMI using the random intercept cross-lagged panel model. Time-varying covariates were pubertal status, stimulant use, depressive symptoms, and family functioning, and socioeconomic status was a time-invariant covariate.RESULTS: We found a time-invariant association of BMI with hyperactivity and impulsivity, but not with inattention, which was slightly stronger in female adolescents (female: r = 0.102; male: r = 0.086, P < .05). No longitudinal direct effects were found between ADHD symptoms and BMI during this period.CONCLUSIONS: Over the course of adolescence, the link between ADHD and BMI is stable and is predominantly with hyperactive and impulsive symptoms rather than inattention. There was no direct effect of ADHD symptoms on BMI increase nor of BMI on enhanced ADHD symptoms during this developmental period. The findings point to a shared genetic or familial background and/or potential causal effects established already earlier in childhood, thus suggesting that intervention and prevention programs targeting overweight and obesity in children with ADHD should be implemented in early childhood.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

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