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Effect of Automated...
Effect of Automated Oxygen Titration during Walking on Dyspnea and Endurance in Chronic Hypoxemic Patients with COPD : A Randomized Crossover Trial
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- Kofod, Linette, 1977- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,PMR-C, Department of Physio- and Occupational Therapy, Copenhagen University Hospital, Hvidovre, Denmark
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- Westerdahl, Elisabeth, 1964- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,University Health Care Research Center
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- Kristensen, Morten Tange (författare)
- PMR-C, Department of Physio- and Occupational Therapy, Copenhagen University Hospital, Hvidovre, Denmark; Department of Orthopaedic Surgery, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark; Department of Physio- and Occupational Therapy, Copenhagen University Hospital, Bispebjerg- Frederiksberg and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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- Brocki, Barbara Cristina (författare)
- Department of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark
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- Ringbæk, Thomas (författare)
- Department of Pulmonology, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark
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- Hansen, Ejvind Frausing (författare)
- Department of Pulmonology, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark
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(creator_code:org_t)
- 2021-10-20
- 2021
- Engelska.
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Ingår i: Journal of Clinical Medicine. - : MDPI. - 2077-0383. ; 10:21
- Relaterad länk:
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https://doi.org/10.3...
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- The need for oxygen increases with activity in patients with COPD and on long-term oxygen treatment (LTOT), leading to periods of hypoxemia, which may influence the patient's performance. This study aimed to evaluate the effect of automated oxygen titration compared to usual fixed-dose oxygen treatment during walking on dyspnea and endurance in patients with COPD and on LTOT. In a double-blinded randomised crossover trial, 33 patients were assigned to use either automated oxygen titration or the usual fixed-dose in a random order in two walking tests. A closed-loop device, O2matic delivered a variable oxygen dose set with a target saturation of 90-94%. The patients had a home oxygen flow of (mean ± SD) 1.6 ± 0.9 L/min. At the last corresponding isotime in the endurance shuttle walk test, the patients reported dyspnea equal to median (IQR) 4 (3-6) when using automated oxygen titration and 8 (5-9) when using fixed doses, p < 0.001. The patients walked 10.9 (6.5-14.9) min with automated oxygen compared to 5.5 (3.3-7.9) min with fixed-dose, p < 0.001. Walking with automated oxygen titration had a statistically significant and clinically important effect on dyspnea. Furthermore, the patients walked for a 98% longer time when hypoxemia was reduced with a more well-matched, personalised oxygen treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- O2matic
- exercise
- long-term oxygen treatment
- physiotherapy
- respiratory failure
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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