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A nationwide cohort...
A nationwide cohort study of the incidence of inflammatory bowel disease in Sweden from 1990 to 2014
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- Forss, Anders (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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- Clements, Mark (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Bergman, David (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Roelstraete, Bjorn (författare)
- Karolinska Institutet,Karolinska Inst, Sweden
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- Kaplan, Gilaad G. (författare)
- University of Calgary, Calgary, AB, Canada,Univ Calgary, Canada
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- Myrelid, Pär (författare)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US
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- Halfvarson, Jonas, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Orebro Univ, Sweden
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- Olén, Ola (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Stockholm South Gen Hosp, Sweden
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- Ludvigsson, Jonas F., 1969- (författare)
- Karolinska Institutet,Karolinska Inst, Sweden; Orebro Univ Hosp, Sweden; Columbia Univ Coll Phys & Surg, NY 10032 USA
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(creator_code:org_t)
- 2021-12-14
- 2022
- Engelska.
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Ingår i: Alimentary Pharmacology and Therapeutics. - : Wiley-Blackwell Publishing Inc.. - 0269-2813 .- 1365-2036. ; 55:6, s. 691-699
- Relaterad länk:
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https://doi.org/10.1...
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https://onlinelibrar...
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Epidemiological studies have shown inconsistent incidence rates (IRs) for inflammatory bowel disease (IBD).AIM: To assess the incidence and temporal trends of IBD in Sweden.METHODS: Nationwide cohort study based on diagnostic codes for IBD and biopsy reports registered through the ESPRESSO cohort in 1990-2014. Age-specific and age-standardised IRs and cumulative incidence were calculated.RESULTS: Overall, we identified 65 908 cases of incident IBD: ulcerative colitis (UC, n = 38 261, 58%), Crohn's disease (CD, n = 18 577, 28%) and IBD-U (n = 9070, 14%). During 1990-2014, the overall IRs per 100 000 person-years were 29.0 (95% CI: 27.3-30.7) for IBD, 16.9 (15.9-17.9) for UC, and 8.1 (7.7-8.6) for CD. For IBD-U, the IR was 5.2 (4.9-5.6) in 2002-2014. The annual incidence of IBD, UC and CD increased by approximately 7% per year between 1990 and 2001 (P < 0.001) and then decreased by 1%-2% per year from 2002 onwards (P < 0.001). IRs for IBD, UC and IBD-U were higher in males while the IR for CD was higher in females. The lifetime risk of IBD was about 2.5% for both sexes.CONCLUSIONS: In Sweden, the incidence of IBD in all subtypes increased in 1990-2001 but has since declined. One in 40 individuals is expected to be diagnosed with IBD during their lifetime.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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