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Microwave-assisted ...
Microwave-assisted extraction of polysaccharides from the marshmallow roots : Optimization, purification, structure, and bioactivity
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- Hashemifesharaki, Reza (författare)
- Mute Hammer LLC, USA
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- Xanthakis, Epameinondas (författare)
- RISE,Jordbruk och livsmedel
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- Altintas, Zeznep (författare)
- Technical University of Berlin, Germany
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- Guo, Ya (författare)
- Jiangnan University, China
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- Gharibzahedi, Seyed (författare)
- Islamic Azad University, Iran
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(creator_code:org_t)
- Elsevier Ltd, 2020
- 2020
- Engelska.
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Ingår i: Carbohydrate Polymers. - : Elsevier Ltd. - 0144-8617 .- 1879-1344. ; 240
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The process optimization and biological characterization of marshmallow root polysaccharides (MRPs) obtained from the microwave-assisted extraction (MAE) were studied. The highest MAE-yield (14.47%) was optimized at 457.32 W and 75 °C for 26 min. The extracted crude polysaccharides were purified using ion-exchange and gel-filtration chromatographies and eluted a single symmetrical narrow peak, showing a homogenous fraction (MRP-P1) with a molecular weight of 4.87 × 104 Da. The surface morphology of polysaccharides and functional groups of MRP-P1 were determined by employing scanning electron microscopy and Fourier-transform infrared spectroscopy, respectively. The major monosaccharide composition of MRPs were the three monomers of rhamnose, galactose, and glucose. The antioxidant, antimicrobial, and antitumor activities were increased in a concentration-dependent manner (1.0-10.0 mg/mL). MRP-P1 exhibited a strong in vitro antiproliferative activity against lung (A549), liver (HepG2), and breast (MCF-7) cancer cells. The anticancer activity of polysaccharides extracted under optimal MAE conditions was highly associated with their antioxidant and antibacterial functions.
Nyckelord
- Althaea officinalis L.
- Biological properties
- Extraction
- FTIR
- Functional properties
- Microwave
- polysaccharide
- Antioxidants
- Fourier transform infrared spectroscopy
- Gel permeation chromatography
- Glucose
- Ion exchange
- Morphology
- Optimization
- Purification
- Scanning electron microscopy
- Surface morphology
- Anti-proliferative activities
- Anti-tumor activities
- Antibacterial functions
- Biological characterization
- Concentration-dependent manners
- Gel-filtration chromatography
- Microwave-assisted extraction
- Monosaccharide composition
- Polysaccharides
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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