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Bone response to su...
Bone response to surface-modified titanium implants : Studies on the early tissue response to implants with different surface characteristics
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- Larsson Wexell, Cecilia, 1965 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,University of Gothenburg, Sweden; Södra Älvsborgs sjukhus, Sweden; Sahlgrenska Academy, Sweden
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- Thomsen, Peter, 1953 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,University of Gothenburg, Sweden; Södra Älvsborgs sjukhus, Sweden; BIOMATCELL, Sweden
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- Aronsson, Björn Owe (författare)
- Chalmers University of Technology, Sweden; Nano Bridging Molecules SA, Switzerland,Chalmers tekniska högskola
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- Tengvall, Pentti (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials,Sahlgrenska Academy, Sweden; BIOMATCELL, Sweden; Linköping University, Sweden
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- Rodahl, Michael (författare)
- Chalmers University of Technology, Sweden,Chalmers tekniska högskola
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- Lausmaa, Jukka (författare)
- Gothenburg University,RISE,SP – Sveriges Tekniska Forskningsinstitut / Funktionella material (KMf),Sahlgrenska Academy, Sweden; BIOMATCELL, Sweden,Göteborgs universitet,University of Gothenburg,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institute of Clinical Sciences, Department of Biomaterials
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- Kasemo, Bengt Herbert, 1942 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Ericson, Lars (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi,Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology
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(creator_code:org_t)
- Hindawi Limited, 2013
- 2013
- Engelska.
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Ingår i: International Journal of Biomaterials. - : Hindawi Limited. - 1687-8787 .- 1687-8795.
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Abstract
Ämnesord
Stäng
- In a series of experimental studies, the bone formation around systematically modified titanium implants is analyzed. In the present study, three different surface modifications were prepared and evaluated. Glow-discharge cleaning and oxidizing resulted in a highly stoichiometric TiO2 surface, while a glow-discharge treatment in nitrogen gas resulted in implants with essentially a surface of titanium nitride, covered with a very thin titanium oxide. Finally, hydrogen peroxide treatment of implants resulted in an almost stoichiometric TiO2, rich in hydroxyl groups on the surface. Machined commercially pure titanium implants served as controls. Scanning Auger Electron Spectroscopy, Scanning Electron Microscopy, and Atomic Force Microscopy revealed no significant differences in oxide thickness or surface roughness parameters, but differences in the surface chemical composition and apparent topography were observed. After surface preparation, the implants were inserted in cortical bone of rabbits and evaluated after 1, 3, and 6 weeks. Light microscopic evaluation of the tissue response showed that all implants were in contact with bone and had a large proportion of newly formed bone within the threads after 6 weeks. There were no morphological differences between the four groups. Our study shows that a high degree of bone contact and bone formation can be achieved with titanium implants of different surface composition and topography.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- hydrogen peroxidehydroxyl group
- nitrogen
- titanium derivative
- titanium dioxide
- titanium nitride
- unclassified drug
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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