Sökning: onr:"swepub:oai:DiVA.org:su-156731" > Probing the Differe...
Fältnamn | Indikatorer | Metadata |
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000 | 03189naa a2200349 4500 | |
001 | oai:DiVA.org:su-156731 | |
003 | SwePub | |
008 | 180618s2018 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1567312 URI |
024 | 7 | a https://doi.org/10.1021/acs.est.7b061282 DOI |
040 | a (SwePub)su | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Shi, Yali4 aut |
245 | 1 0 | a Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalkyl Substances of Varying Chain-Lengths, Isomeric Structures and Functional Groups in Crucian Carp |
264 | c 2018-04-03 | |
264 | 1 | b American Chemical Society (ACS),c 2018 |
338 | a print2 rdacarrier | |
520 | a Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point sources can provide information about the processes governing uptake, distribution and elimination of PFASs. Median tissue/blood ratios (TBRs) were consistently <1 for all PFASs and tissues except bile which displayed a distinct distribution pattern and enrichment of several perfluoroalkyl sulfonic acids. Transformation of concentration data into relative body burdens (RBBs) demonstrated that blood, gonads, and muscle together accounted for >90% of the amount of PFASs in the organism. Principal component analyses of TBRs and RBBs showed that the functional group was a relatively more important predictor of internal distribution than chain length for PFASs. Whole body bioaccumulation factors (BAFs) for short-chain PFASs deviated from the positive relationship with hydrophobicity observed for longer-chain homologues. Overall, our results suggest that TBR, RBB, and BAF patterns were most consistent with protein binding mechanisms although partitioning to phospholipids may contribute to the accumulation of long-chain PFASs in specific tissues. | |
650 | 7 | a NATURVETENSKAPx Geovetenskap och miljövetenskap0 (SwePub)1052 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Earth and Related Environmental Sciences0 (SwePub)1052 hsv//eng |
700 | 1 | a Vestergren, Robinu Stockholms universitet,Institutionen för miljövetenskap och analytisk kemi,IVL Swedish Environmental Research Institute, Sweden4 aut0 (Swepub:su)rove0027 |
700 | 1 | a Haugdahl Nost, Therese4 aut |
700 | 1 | a Zhou, Zhen4 aut |
700 | 1 | a Cai, Yaqi4 aut |
710 | 2 | a Stockholms universitetb Institutionen för miljövetenskap och analytisk kemi4 org |
773 | 0 | t Environmental Science and Technologyd : American Chemical Society (ACS)g 52:8, s. 4592-4600q 52:8<4592-4600x 0013-936Xx 1520-5851 |
856 | 4 | u https://pubs.acs.org/doi/pdf/10.1021/acs.est.7b06128 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-156731 |
856 | 4 8 | u https://doi.org/10.1021/acs.est.7b06128 |
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