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SYNTHESIS, ANTIMICR...
SYNTHESIS, ANTIMICROBIAL ACTIVITY, UREASE INHIBITION AND MOLECULAR DOCKING STUDIES OF NEW PROLINE LINKED THIOUREA DERIVATIVES
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Raheel, Ahmad (författare)
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Iftikhar, Syed Hassan (författare)
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Taj, Muhammad Babar (författare)
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- Ayub, Rabia (författare)
- Stockholms universitet,Institutionen för organisk kemi
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Zafar, Anham (författare)
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Abbas, Sumaira (författare)
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Al-Shakban, Mundher (författare)
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(creator_code:org_t)
- 2020
- 2020
- Engelska.
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Ingår i: Revue roumaine de chimie. - : Romanian Academy - Revue Roumaine De Chimie. - 0035-3930. ; 65:9, s. 783-788
- Relaterad länk:
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https://doi.org/10.3...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- A series of new thiourea based carboxylic acids (I-a-I-e) were synthesized and characterized by elemental analysis, FTIR and NMR (H-1 and C-13) spectroscopy. They were preliminary bioassayed for their antibacterial, anifungal and urease inhibition activities. Molecular docking simulations were carried out to determine the probable binding mode of the synthesized compounds. The bioassay results showed that some of titled compounds exhibited encouraging results.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Nyckelord
- antimicrobial
- enzyme inhibition
- molecular docking
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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