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Predicting sample s...
Predicting sample success for large-scale ancient DNA studies on marine mammals
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- Keighley, Xénia (författare)
- University of Groningen,University of Copenhagen
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- Bro-Jørgensen, Maiken Hemme (författare)
- Stockholm University,Stockholms universitet,Arkeologiska forskningslaboratoriet,University of Copenhagen, Denmark
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- Ahlgren, Hans (författare)
- Stockholm University,Stockholms universitet,Arkeologiska forskningslaboratoriet
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- Szpak, Paul (författare)
- Trent University
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- Ciucani, Marta Maria (författare)
- University of Copenhagen
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- Sánchez Barreiro, Fátima (författare)
- University of Copenhagen
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- Howse, Lesley (författare)
- University of Toronto
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- Gotfredsen, Anne Birgitte (författare)
- University of Copenhagen
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- Glykou, Aikaterini (författare)
- Stockholm University,Stockholms universitet,Arkeologiska forskningslaboratoriet
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- Jordan, Peter (författare)
- Lund University,Lunds universitet,Arkeologi,Institutionen för arkeologi och antikens historia,Institutioner,Humanistiska och teologiska fakulteterna,Archaeology,Department of Archaeology and Ancient History,Departments,Joint Faculties of Humanities and Theology
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- Lidén, Kerstin (författare)
- Stockholm University,Stockholms universitet,Arkeologiska forskningslaboratoriet
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- Olsen, Morten Tange (författare)
- University of Copenhagen
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(creator_code:org_t)
- 2021-02-26
- 2021
- Engelska.
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Ingår i: Molecular Ecology Resources. - : Wiley. - 1755-098X .- 1755-0998. ; 21:4, s. 1149-1166
- Relaterad länk:
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https://doi.org/10.1...
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https://su.diva-port... (primary) (Raw object)
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https://onlinelibrar...
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- In recent years, non-human ancient DNA studies have begun to focus on larger sample sizes and whole genomes, offering the potential to reveal exciting and hitherto unknown answers to ongoing biological and archaeological questions. However, one major limitation to the feasibility of such studies is the substantial financial and time investments still required during sample screening, due to uncertainty regarding successful sample selection. This study investigates the effect of a wide range of sample properties including latitude, sample age, skeletal element, collagen preservation, and context on endogenous content and DNA damage profiles for 317 ancient and historic pinnipedsamples collected from across the North Atlantic. Using generalised linear and mixed-effectmodels, we found that a range of factors affected DNA preservation within each of the species under consideration. The most important findings were that endogenous content varied significantly according to context, the type of skeletal element, the collagen content and collection year. There also appears to be an effect of the sample’s geographic origin, with samples from the Arcticgenerally showing higher endogenous content and lower damage rates. Both latitude and sample age were found to have significant relationships with damage levels, but only for walrus samples. Sex, ontogenetic age and extraction material preparation were not found to have any significantrelationship with DNA preservation. Overall, the skeletal element and sample context were found to be the most influential factors and should therefore be considered when selecting samples for large-scale ancient genome studies.
Ämnesord
- HUMANIORA -- Historia och arkeologi (hsv//swe)
- HUMANITIES -- History and Archaeology (hsv//eng)
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Nyckelord
- Endogenous content
- DNA damage
- zooarchaeology
- sample age
- pinnipeds
- aDNA
- walrus
- seal
- Genetics
- genetik
- Scientific Archaeology
- arkeologi med inriktning mot laborativ arkeologi
- aDNA
- DNA damage
- endogenous content
- pinnipeds
- sample age
- seal
- walrus
- zooarchaeology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Keighley, Xénia
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Bro-Jørgensen, M ...
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Ahlgren, Hans
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Szpak, Paul
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Ciucani, Marta M ...
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Sánchez Barreiro ...
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visa fler...
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Howse, Lesley
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Gotfredsen, Anne ...
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Glykou, Aikateri ...
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Jordan, Peter
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Lidén, Kerstin
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Olsen, Morten Ta ...
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visa färre...
- Om ämnet
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- HUMANIORA
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HUMANIORA
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och Historia och ark ...
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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- NATURVETENSKAP
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NATURVETENSKAP
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och Biologi
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och Genetik
- Artiklar i publikationen
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Molecular Ecolog ...
- Av lärosätet
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Stockholms universitet
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Lunds universitet