Sökning: onr:"swepub:oai:DiVA.org:su-22322" > NMR solution struct...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 02669naa a2200505 4500 | |
001 | oai:DiVA.org:su-22322 | |
003 | SwePub | |
008 | 070612s2004 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-223222 URI |
040 | a (SwePub)su | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bárány-Wallje, Elsau Stockholms universitet,Institutionen för biokemi och biofysik,biofysik,Astrid Gräslund4 aut0 (Swepub:su)ebr |
245 | 1 0 | a NMR solution structure and position of transportan in neutral phospholipid bicelles. |
264 | 1 | c 2004 |
338 | a print2 rdacarrier | |
520 | a Transportan is a chimeric cell-penetrating peptide constructed from the peptides galanin and mastoparan, which has the ability to internalize living cells carrying a hydrophilic load. In this study, we have determined the NMR solution structure and investigated the position of transportan in neutral bicelles. The structure revealed a well-defined -helix in the C-terminal mastoparan part of the peptide and a weaker tendency to form an -helix in the N-terminal domain. The position of the peptide in relation to the membrane, as studied by adding paramagnetic probes, shows that the peptide lies parallel to, and in the head-group region of the membrane surface. This result is supported by amide proton secondary chemical shifts. | |
653 | a Amides/chemistry | |
653 | a Amino Acid Sequence | |
653 | a Circular Dichroism | |
653 | a Dimyristoylphosphatidylcholine/*chemistry | |
653 | a Drug Carriers/chemistry | |
653 | a Galanin | |
653 | a Glycerophosphates/chemistry | |
653 | a Lipid Bilayers/*chemistry | |
653 | a Micelles | |
653 | a Models; Molecular | |
653 | a Molecular Sequence Data | |
653 | a Nuclear Magnetic Resonance; Biomolecular/*methods | |
653 | a Phospholipid Ethers/*chemistry | |
653 | a Phosphorylcholine/*analogs & derivatives/chemistry | |
653 | a Protein Structure; Secondary | |
653 | a Protein Structure; Tertiary | |
653 | a Recombinant Fusion Proteins/*chemistry | |
653 | a Spin Labels | |
653 | a Wasp Venoms | |
700 | 1 | a Andersson, August4 aut |
700 | 1 | a Gräslund, Astrid4 aut |
700 | 1 | a Mäler, Lena4 aut |
710 | 2 | a Stockholms universitetb Institutionen för biokemi och biofysik4 org |
773 | 0 | t FEBS Lettg 567:2-3, s. 265-9q 567:2-3<265-9x 0014-5793 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15178334&dopt=Citation |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-22322 |
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