Sökning: onr:"swepub:oai:DiVA.org:su-34528" > Structural Correlat...
Fältnamn | Indikatorer | Metadata |
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000 | 03804naa a2200541 4500 | |
001 | oai:DiVA.org:su-34528 | |
003 | SwePub | |
008 | 100109s2009 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:119530010 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-345282 URI |
024 | 7 | a https://doi.org/10.1542/peds.2008-38012 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1195300102 URI |
040 | a (SwePub)sud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Nagy, Zoltan4 aut |
245 | 1 0 | a Structural Correlates of Preterm Birth in the Adolescent Brain |
264 | c 2009-11-01 | |
264 | 1 | b American Academy of Pediatrics,c 2009 |
338 | a print2 rdacarrier | |
520 | a OBJECTIVE: The Stockholm Neonatal Project involves a prospective,cross-sectional, population-based, cohort monitored for 12 to17 years after birth; it was started with the aim of investigatingthe long-term structural correlates of preterm birth and comparingfindings with reports on similar cohorts.METHODS: High-resolution anatomic and diffusion tensor imagingdata measuring diffusion in 30 directions were collected byusing a 1.5-T MRI scanner. A total of 143 adolescents (12.18–17.7years of age) participated in the study, including 74 formerlypreterm infants with birth weights of 1500 g (range: 645–1486g) and 69 term control subjects. The 2 groups were well matchedwith respect to demographic and socioeconomic data. The anatomicMRI data were used for calculation of total brain volumes andvoxelwise comparison of gray matter (GM) volumes. The diffusiontensor imaging data were used for voxelwise comparison of whitematter (WM) microstructural integrity.RESULTS: The formerly preterm individuals possessed 8.8% smallerGM volume and 9.4% smaller WM volume. The GM and WM volumesof individuals depended on gestational age and birth weight.The reduction in GM could be attributed bilaterally to the temporallobes, central, prefrontal, orbitofrontal, and parietal cortices,caudate nuclei, hippocampi, and thalami. Lower fractional anisotropywas observed in the posterior corpus callosum, fornix, and externalcapsules.CONCLUSIONS: Although preterm birth was found to be a risk factorregarding long-term structural brain development, the outcomewas milder than in previous reports. This may be attributableto differences in social structure and neonatal care practices. | |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
653 | a preterm | |
653 | a magnetic resonance imaging | |
653 | a brain | |
653 | a diffusion tensor imaging | |
653 | a follow-up evaluation | |
653 | a Psychology | |
653 | a Psykologi | |
653 | a Psychology | |
653 | a psykologi | |
700 | 1 | a Ashburner, John4 aut |
700 | 1 | a Andersson, Jesper4 aut |
700 | 1 | a Jbabdi, Saad4 aut |
700 | 1 | a Draganski, Bogdan4 aut |
700 | 1 | a Skare, Stefanu Karolinska Institutet4 aut |
700 | 1 | a Böhm, Birgittau Karolinska Institutet4 aut |
700 | 1 | a Smedler, Ann-Charlotteu Stockholms universitet,Psykologiska institutionen4 aut0 (Swepub:su)acsr |
700 | 1 | a Forssberg, Hansu Karolinska Institutet4 aut |
700 | 1 | a Lagercrantz, Hugou Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutetb Psykologiska institutionen4 org |
773 | 0 | t Pediatricsd : American Academy of Pediatricsg 124:5, s. e964-e972q 124:5<e964-e972x 0031-4005x 1098-4275 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-34528 |
856 | 4 8 | u https://doi.org/10.1542/peds.2008-3801 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:119530010 |
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