Sökning: onr:"swepub:oai:DiVA.org:su-51344" > NordicDB :
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04890naa a2200769 4500 | |
001 | oai:DiVA.org:su-51344 | |
003 | SwePub | |
008 | 110110s2010 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:fe38d2b3-8f1a-4fd0-a8ad-e28c6c6fec61 | |
009 | oai:prod.swepub.kib.ki.se:121610066 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-513442 URI |
024 | 7 | a https://doi.org/10.1038/ejhg.2010.1122 DOI |
024 | 7 | a https://lup.lub.lu.se/record/17524962 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1216100662 URI |
040 | a (SwePub)sud (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Leu, Monica4 aut |
245 | 1 0 | a NordicDB :b a Nordic pool and portal for genome-wide control data |
264 | c 2010-07-28 | |
264 | 1 | b Springer Science and Business Media LLC,c 2010 |
338 | a print2 rdacarrier | |
500 | a authorCount :19 | |
520 | a A cost-efficient way to increase power in a genetic association study is to pool controls from different sources. The genotyping effort can then be directed to large case series. The Nordic Control database, NordicDB, has been set up as a unique resource in the Nordic area and the data are available for authorized users through the web portal (http://www.nordicdb.org). The current version of NordicDB pools together high-density genome-wide SNP information from similar to 5000 controls originating from Finnish, Swedish and Danish studies and shows country-specific allele frequencies for SNP markers. The genetic homogeneity of the samples was investigated using multidimensional scaling (MDS) analysis and pairwise allele frequency differences between the studies. The plot of the first two MDS components showed excellent resemblance to the geographical placement of the samples, with a clear NW-SE gradient. We advise researchers to assess the impact of population structure when incorporating NordicDB controls in association studies. This harmonized Nordic database presents a unique genome-wide resource for future genetic association studies in the Nordic countries. European Journal of Human Genetics (2010) 18, 1322-1326; doi: 10.1038/ejhg.2010.112; published online 28 July 2010 | |
650 | 7 | a NATURVETENSKAPx Matematik0 (SwePub)1012 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Mathematics0 (SwePub)1012 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
653 | a common controls | |
653 | a genome-wide data | |
653 | a Nordic Control Database | |
653 | a population stratification | |
653 | a MATHEMATICS | |
653 | a MATEMATIK | |
653 | a population | |
653 | a stratification | |
653 | a Nordic Control Database | |
653 | a common controls | |
653 | a genome-wide data | |
700 | 1 | a Humphreys, Keithu Karolinska Institutet4 aut |
700 | 1 | a Surakka, Ida4 aut |
700 | 1 | a Rehnberg, Emil4 aut |
700 | 1 | a Muilu, Juha4 aut |
700 | 1 | a Rosenstrom, Paivi4 aut |
700 | 1 | a Almgren, Peteru Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-pal |
700 | 1 | a Jaaskelainen, Juhau Karolinska Institutet4 aut |
700 | 1 | a Lifton, Richard P.4 aut |
700 | 1 | a Kyvik, Kirsten Ohm4 aut |
700 | 1 | a Kaprio, Jaakko4 aut |
700 | 1 | a Pedersen, Nancy L.u Karolinska Institutet4 aut |
700 | 1 | a Palotie, Aarno4 aut |
700 | 1 | a Hall, Peru Karolinska Institutet4 aut |
700 | 1 | a Gronberg, Henriku Karolinska Institutet4 aut |
700 | 1 | a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr |
700 | 1 | a Peltonen, Leena4 aut |
700 | 1 | a Palmgren, Juniu Stockholms universitet,Matematiska institutionen4 aut0 (Swepub:su)juni |
700 | 1 | a Ripatti, Samuli4 aut |
710 | 2 | a Karolinska Institutetb Genomik, diabetes och endokrinologi4 org |
773 | 0 | t European Journal of Human Geneticsd : Springer Science and Business Media LLCg 18:12, s. 1322-1326q 18:12<1322-1326x 1018-4813x 1476-5438 |
856 | 4 | u https://www.nature.com/articles/ejhg2010112.pdf |
856 | 4 | u http://dx.doi.org/10.1038/ejhg.2010.112y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-51344 |
856 | 4 8 | u https://doi.org/10.1038/ejhg.2010.112 |
856 | 4 8 | u https://lup.lub.lu.se/record/1752496 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:121610066 |
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