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Prevalence of colon...
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Forsberg, Anna M.Karolinska Institutet
(författare)
Prevalence of colonic neoplasia and advanced lesions in the normal population : a prospective population-based colonoscopy study
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
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2012-01-10
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Informa UK Limited,2012
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:su-70929
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-70929URI
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https://doi.org/10.3109/00365521.2011.647062DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:123906038URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Objective. There are few prospective studies of the prevalence of colonic neoplasia in the normal population. In order to properly evaluate screening-protocols for colorectal cancer in risk groups (e.g., older subjects or those with a family history), it is essential to know the prevalence of adenomas and cancer in the normal population. Methods. A prospective population-based colonoscopy study on 745 individuals born in Sweden aged 19-70 years was conducted (mean age 51.1 years). All polyps seen were retrieved and examined. Results. Out of the 745 individuals 27% had polyps, regardless of kind. Adenomas were found in 10% of the individuals and finding of adenomas was positively correlated to higher age. Men had adenomas in 15% and women in 6% of the cases. Women had a right-sided dominance of adenomas. Hyperplastic polyps were seen in 21% of the individuals. The presence of hyperplastic polyps was significantly positively correlated to the presence of adenomas. Advanced adenomas were seen in 2.8% of the study participants, but no cancers were detected. Conclusion. One in 10 healthy subjects had an adenoma but advanced adenomas were uncommon. Men and women have a different adenoma prevalence and localization. The results provide baseline European data for evaluating colonoscopy screening-protocols for colorectal cancer risk groups, and the findings may have implications for colon cancer screening in the normal, otherwise-healthy population.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Kjellström, Lars
(författare)
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Agréus, LarsKarolinska Institutet
(författare)
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Nixon Andreasson, AnnaKarolinska Institutet,Stockholms universitet,Stressforskningsinstitutet(Swepub:su)anan6088
(författare)
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Nyhlin, Henry
(författare)
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Talley, Nicholas J.
(författare)
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Björck, ErikKarolinska Institutet
(författare)
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Karolinska InstitutetStressforskningsinstitutet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Scandinavian journal of gastroenterology: Informa UK Limited47:2, s. 184-901502-77080036-5521
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