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Theoretical simulat...
Theoretical simulation of tumour oxygenation--practical applications
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- Daşu, Alexandru (författare)
- Umeå universitet,Radiofysik,Umeå University
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- Toma-Dasu, Iuliana (författare)
- Umeå universitet,Radiofysik,Umeå University
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Cicco, G (författare)
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Bruley, DF (författare)
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Ferrari, M (författare)
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Harrison, DK (författare)
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(creator_code:org_t)
- Springer US, 2006
- 2006
- Engelska.
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Ingår i: Advances in Experimental Medicine and Biology. - : Springer US. - 0065-2598 .- 2214-8019. ; 578, s. 357-362
- Relaterad länk:
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Theoretical simulation of tissue oxygenation is a robust method that can be used to quantify the tissue oxygenation for a variety of applications. However, it is necessary that the relevant input parameters are used for the model describing the tumour microenvironment. The results of the simulations presented in this article suggest that the accuracy of the simulations depends very much on the method of calculation of the effects of the temporal change of the hypoxic pattern due to the opening and the closure of blood vessels. Thus, the use of average oxygenations might lead to dangerous overestimations of the treatment response. This indicates that care should be taken when incorporating hypoxia information into the biological modelling of tumour response.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Radiation Physics
- radiofysik
- Medical Radiation Physics
- medicinsk strålningsfysik
- Oncology
- onkologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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