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Carotid plaque echo...
Carotid plaque echogenicity predicts cerebrovascular symptoms : a systematic review and meta-analysis
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- Jashari, Fisnik (författare)
- Umeå universitet,Kardiologi
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- Ibrahimi, Pranvera (författare)
- Umeå universitet,Kardiologi
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- Bajraktari, Gani (författare)
- Umeå universitet,Kardiologi
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- Grönlund, Christer (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Wester, Per (författare)
- Karolinska Institutet,Umeå universitet,Avdelningen för medicin,Department of Clinical Sciences, Danderyds Hospital, Karolinska Institute, Stockholm, Sweden
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- Henein, Michael Y (författare)
- Umeå universitet,Kardiologi
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(creator_code:org_t)
- 2016-04-23
- 2016
- Engelska.
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Ingår i: European Journal of Neurology. - : Wiley. - 1351-5101 .- 1468-1331. ; 23:7, s. 1241-1247
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background and purpose: Many reports have shown an association between hypoechoic (echolucent) carotid atherosclerotic plaques and unstable features. In this meta-analysis our aim was to determine the role of carotid plaque echogenicity in predicting future cerebrovascular (CV) symptoms.Methods: Electronic databases (PubMed, MEDLINE, EMBASE and Cochrane Center Register) up to September 2015 were systematically searched. Studies with ultrasound-based characterization of carotid artery plaque echogenicity and its association with focal neurological symptoms of vascular origin were eligible for analysis. In the meta-analysis, heterogeneity was measured usingI2 statistics and publication bias was evaluated using the Begg–Mazumdar test. In addition several comparisons between subgroups were performed.Results: Of 1387 identified reports, eight studies with asymptomatic patients and three studies with symptomatic patients were meta-analyzed. Pooled analysis showed an association between echolucent carotid plaques and future CV events in asymptomatic patients [relative risk 2.72 (95% confidence interval 1.86–3.96)] and recurrent symptoms in symptomatic patients [relative risk 2.97 (95% confidence interval 1.85–4.78)]. The association was preserved for all stenosis degrees in asymptomatic patients, whilst patients with echolucent plaques and severe stenosis were at higher risk of future events. Also, computer-assisted methods for assessment of carotid plaque echogenicity and studies analyzing ultrasound data collected after the year 2000 showed better prediction.Conclusions: In asymptomatic and symptomatic patients, analysis of carotid plaque echogenicity could identify those at high risk of CV events.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- carotid atherosclerosis
- cerebrovascular symptoms
- grey scale median
- plaque echogenicity
- trasound
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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