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Carotid plaque echo...
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Jashari, FisnikUmeå universitet,Kardiologi
(författare)
Carotid plaque echogenicity predicts cerebrovascular symptoms : a systematic review and meta-analysis
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
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2016-04-23
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Wiley,2016
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:umu-124230
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124230URI
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https://doi.org/10.1111/ene.13017DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:133816872URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Background and purpose: Many reports have shown an association between hypoechoic (echolucent) carotid atherosclerotic plaques and unstable features. In this meta-analysis our aim was to determine the role of carotid plaque echogenicity in predicting future cerebrovascular (CV) symptoms.Methods: Electronic databases (PubMed, MEDLINE, EMBASE and Cochrane Center Register) up to September 2015 were systematically searched. Studies with ultrasound-based characterization of carotid artery plaque echogenicity and its association with focal neurological symptoms of vascular origin were eligible for analysis. In the meta-analysis, heterogeneity was measured usingI2 statistics and publication bias was evaluated using the Begg–Mazumdar test. In addition several comparisons between subgroups were performed.Results: Of 1387 identified reports, eight studies with asymptomatic patients and three studies with symptomatic patients were meta-analyzed. Pooled analysis showed an association between echolucent carotid plaques and future CV events in asymptomatic patients [relative risk 2.72 (95% confidence interval 1.86–3.96)] and recurrent symptoms in symptomatic patients [relative risk 2.97 (95% confidence interval 1.85–4.78)]. The association was preserved for all stenosis degrees in asymptomatic patients, whilst patients with echolucent plaques and severe stenosis were at higher risk of future events. Also, computer-assisted methods for assessment of carotid plaque echogenicity and studies analyzing ultrasound data collected after the year 2000 showed better prediction.Conclusions: In asymptomatic and symptomatic patients, analysis of carotid plaque echogenicity could identify those at high risk of CV events.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ibrahimi, PranveraUmeå universitet,Kardiologi(Swepub:umu)prib0001
(författare)
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Bajraktari, GaniUmeå universitet,Kardiologi(Swepub:umu)gaba0006
(författare)
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Grönlund, ChristerUmeå universitet,Institutionen för strålningsvetenskaper(Swepub:umu)chgr0009
(författare)
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Wester, PerKarolinska Institutet,Umeå universitet,Avdelningen för medicin,Department of Clinical Sciences, Danderyds Hospital, Karolinska Institute, Stockholm, Sweden(Swepub:umu)pewe0002
(författare)
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Henein, Michael YUmeå universitet,Kardiologi(Swepub:umu)mihe0015
(författare)
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Umeå universitetKardiologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Journal of Neurology: Wiley23:7, s. 1241-12471351-51011468-1331
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