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Probiotics for trea...
Probiotics for treatment and primary prevention of allergic diseases and asthma : looking back and moving forward
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- West, Christina E. (författare)
- Umeå universitet,Pediatrik,International inflammation (in-FLAME) network of the World Universities Network,World University of Network, Sweden; Umeå University, Sweden
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- Jenmalm, Maria (författare)
- Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,World University of Network, Sweden
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- Kozyrskyj, Anita L. (författare)
- World University of Network, Sweden; University of Alberta, Canada
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- Prescott, Susan L. (författare)
- World University of Network, Sweden; University of Western Australia, Australia
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(creator_code:org_t)
- Taylor & Francis, 2016
- 2016
- Engelska.
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Ingår i: Expert Review of Clinical Immunology. - : Taylor & Francis. - 1744-666X .- 1744-8409. ; 12:6, s. 625-639
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Microbial ecosystems cover the surface of the human body and it is becoming increasingly clear that our modern environment has profound effects on microbial composition and diversity. A dysbiotic gut microbiota has been associated with allergic diseases and asthma in cross-sectional and observational studies. In an attempt to restore this dysbiosis, probiotics have been evaluated in randomized controlled trials. Here, we review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context. Many meta-analyses have shown a moderate benefit of probiotics for eczema prevention, whereas there is less evidence of a benefit for other allergic manifestations. Because of very low quality evidence and heterogeneity between studies, specific advice on the most effective regimens cannot yet be given -not even for eczema prevention. To be able to adopt results into specific recommendations, international expert organizations stress the need for well-designed studies.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- Diversity
- dysbiosis
- eczema
- gut microbiome
- hygiene hypothesis
- primary prevention
- probiotic
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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