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Sökning: onr:"swepub:oai:DiVA.org:umu-144945" > Fibre intake and th...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004451naa a2200685 4500
001oai:DiVA.org:umu-144945
003SwePub
008180222s2018 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1449452 URI
024a https://doi.org/10.1093/ecco-jcc/jjx1362 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Andersen, Vibeke4 aut
2451 0a Fibre intake and the development of inflammatory bowel disease :b A European prospective multi-centre cohort study (EPIC-IBD)
264 c 2017-10-07
264 1b OXFORD UNIV PRESS,c 2018
338 a electronic2 rdacarrier
520 a Background and Aims: Population-based prospective cohort studies investigating fibre intake and development of inflammatory bowel disease are lacking. Our aim was to investigate the association between fibre intake and the development of Crohn's disease [CD] and ulcerative colitis [UC] in a large European population.Methods: In total, 401 326 participants, aged 20-80 years, were recruited in eight countries in Europe between 1991 and 1998. At baseline, fibre intake [total fibres, fibres from fruit, vegetables and cereals] was recorded using food frequency questionnaires. The cohort was monitored for the development of inflammatory bowel disease. Each case was matched with four controls and odds ratios [ORs] for the exposures were calculated using conditional logistic regression. Sensitivity analyses according to smoking status were computed.Results: In total, 104 and 221 participants developed incident CD and UC, respectively. For both CD and UC, there were no statistically significant associations with either quartiles, or trends across quartiles, for total fibre or any of the individual sources. The associations were not affected by adjusting for smoking and energy intake. Stratification according to smoking status showed null findings apart from an inverse association with cereal fibre and CD in non-smokers [Quartile 4 vs 1 OR = 0.12, 95% confidence interval = 0.02-0.75, p = 0.023, OR trend across quartiles = 0.50, 95% confidence interval = 0.29-0.86, p = 0.017].Conclusion: The results do not support the hypothesis that dietary fibre is involved in the aetiology of UC, although future work should investigate whether there may be a protective effect of specific types of fibre according to smoking status in CD.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Dietary fibre
653 a diet
653 a epidemiology
653 a fibre food
653 a inflammatory bowel disease
653 a prospective study
700a Chan, Simon4 aut
700a Luben, Robert4 aut
700a Khaw, Kay-Tee4 aut
700a Olsen, Anja4 aut
700a Tjonneland, Anne4 aut
700a Kaaks, R.4 aut
700a Grip, Olof4 aut
700a Bergmann, M. M.4 aut
700a Boeing, H.4 aut
700a Hultdin, Johanu Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)johu0007
700a Karling, Pontusu Umeå universitet,Avdelningen för medicin4 aut0 (Swepub:umu)peakag84
700a Overvad, Kim4 aut
700a Oldenburg, Bas4 aut
700a Opstelten, Jorrit4 aut
700a Boutron-Ruault, Marie-Christine4 aut
700a Carbonnel, Franck4 aut
700a Racine, Antoine4 aut
700a Key, Timothy4 aut
700a Masala, Giovanna4 aut
700a Palli, Domenico4 aut
700a Tumino, R.4 aut
700a Trichopoulou, A.4 aut
700a Riboli, Elio4 aut
700a Hart, Andrew4 aut
710a Umeå universitetb Klinisk kemi4 org
773t Journal of Crohn's & Colitisd : OXFORD UNIV PRESSg 12:2, s. 129-136q 12:2<129-136x 1873-9946x 1876-4479
856u https://doi.org/10.1093/ecco-jcc/jjx136y Fulltext
856u https://umu.diva-portal.org/smash/get/diva2:1184991/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u https://academic.oup.com/ecco-jcc/article-pdf/12/2/129/24365646/jjx136.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-144945
8564 8u https://doi.org/10.1093/ecco-jcc/jjx136

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