Protein nanosheet mechanics controls cell adhesion and expansion on low-viscosity liquids

• Adherent cell culture typically requires cell spreading at the surface of solid substrates to sustain the formation of stable focal adhesions and assembly of a contractile cytoskeleton. However, a few reports have demonstrated that cell culture is possible on liquid substrates such as silicone and fluorinated oils, even displaying very low viscosities (0.77 cSt). Such behavior is surprising as low viscosity liquids are thought to relax much too fast (

Ämnesord

NATURVETENSKAP  -- Kemi -- Annan kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Other Chemistry Topics (hsv//eng)

Nyckelord

cell adhesion

interfacial mechanics

liquid−liquid interface

nanosheets

Protein self-assembly

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)