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Infusion technique ...
Infusion technique can be used to distinguish between dysfunction of a hydrocephalus shunt system and a progressive dementia
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- Eklund, Anders (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Lundkvist, B. (författare)
- Umeå universitet,Neurologi
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- Koskinen, Lars-Owe D., Professor, 1955- (författare)
- Umeå universitet,Neurokirurgi
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- Malm, J (författare)
- Umeå universitet,Neurologi
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(creator_code:org_t)
- Springer, 2004
- 2004
- Engelska.
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Ingår i: Medical and Biological Engineering and Computing. - : Springer. - 0140-0118 .- 1741-0444. ; 42:5, s. 644-649
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In a deteriorating shunted patient with hydrocephalus, an investigation of shunt function is often performed to distinguish a dysfunctioning shunt from an aggravated condition of the disease. The paper illustrates how a lumbar cerebrospinal fluid (CSF) infusion method can be used to evaluate post-operative deterioration in a shunted patient in order to give the physician valuable support in the shunt revision decision. A 77-year-old man with hydrocephalus was treated operatively by the insertion of a CSF shunt. Owing to shunt failure, the shunt was revised twice during a 5 year period. Using a computerised infusion technique method, with two needles placed in the lumbar subarachnoid space, the CSF dynamic system was determined pre- and post-operatively with the functioning as well as the dysfunctioning shunts. The data were verified with a bench-test of the extirpated CSF shunt. There was a significant difference in conductance G between CSF systems with an open shunt and CSF systems with no shunt or an occluded shunt (ΔG=38mm3 s−1 kPa−1, p=0.014, n=7, ANOVA). CSF dynamics investigations, with and without a shunt, can give valuable clinical support in the management of a deteriorating hydrocephalus patient. With further development of the lumbar infusion method moving towards easy-to-use equipment, there is potential for widespread clinical use.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Hydrocephalus
- intracranial pressure
- cerebrospinal fluid
- shunt
- infusion
- normal pressure hydrocephalus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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