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Prevalence of comor...
Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus : a retrospective study
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Alqahtani, F. Y. (författare)
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Aleanizy, F. S. (författare)
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Mohamed, R. Ali El Hadi (författare)
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Alanazi, M. S. (författare)
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- Mohamed, Nahla (författare)
- Umeå universitet,Virologi,College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 12484, Saudi Arabia
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Alrasheed, M. M. (författare)
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Abanmy, N. (författare)
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Alhawassi, T. (författare)
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(creator_code:org_t)
- Cambridge University Press, 2019
- 2019
- Engelska.
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Ingår i: Epidemiology and Infection. - : Cambridge University Press. - 0950-2688 .- 1469-4409. ; 147
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We aimed to explore the influence of demographic factors, clinical manifestations and underlying comorbidities on mortality in MERS-CoV patients. Retrospective chart reviews were performed to identify all laboratory-confirmed cases of MERS-COV infection in Saudi Arabia that were reported to the Ministry of Health of Saudi Arabia between 23 April 2014 and 7 June 2016. Statistical analyses were conducted to assess the effect of sex, age, clinical presentation and comorbidities on mortality from MERS-CoV. A total of 281 confirmed MERS-CoV cases were identified: 167 (59.4%) patients were male and 55 (20%) died. Mortality predominantly occurred among Saudi nationals and older patients and was significantly associated with respiratory failure and shortness of breath. Of the 281 confirmed cases, 160 (56.9%) involved comorbidities, wherein diabetes mellitus, hypertension, ischemic heart disease, congestive heart failure, end-stage renal disease and chronic kidney disease were significantly associated with mortality from MERS-CoV and two or three comorbidities significantly affected the fatality rates from MERS-CoV. The findings of this study show that old age and the existence of underlying comorbidities significantly increase mortality from MERS-CoV.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Comorbidities
- middle east respiratory syndrome coronavirus
- mortality
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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