Sökning: onr:"swepub:oai:DiVA.org:umu-156008" >
Physical activity a...
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Carsin, Anne-ElieCtr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
(författare)
Physical activity and incidence of restrictive spirometry pattern in adults
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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European Respiratory Society,2018
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:umu-156008
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-156008URI
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https://doi.org/10.1183/13993003.congress-2018.PA5289DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-376322URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:vet swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Supplement: 62Meeting Abstract: PA5289
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Introduction: A restrictive spirometry pattern is associated with high morbidity and mortality. Whether regular physical activity (PA) protects against this pattern has never been studied.Objective: To assess if PA is associated with the development of restrictive pattern.Methods: Lung function and PA were assessed in the second and third follow-up of the ECRHS (n=2757, 39-67 years) and SAPALDIA (n=2610, 36-82 y) cohorts. Subjects with restrictive or obstructive pattern at baseline were excluded. We assessed the association of being active at baseline (defined as exercising vigorously >2-3 times/wk for >1 h) and restrictive pattern at follow-up (defined as a post-bronchodilator FEV1/FVC≥LLN and FVC<80% pred.) using modified Poisson regression, adjusting for age, sex, smoking and asthma. We explored the impact of adjusting for baseline FVC. Additionally, models were repeated stratified by BMI.Results: After 10 years follow-up, 3.7% and 2.8% of participants developed a restrictive pattern, in ECRHS and SAPALDIA respectively. In both cohorts, being physically active was associated with lower risk of a restrictive pattern (meta-analysed RR 0.65, 95% CI 0.47-0.89). This association was stronger in overweight (0.41, 0.23-0.75) and obese (0.42, 0.17-1.05) than in normal weight subjects, but was attenuated when adjusting for baseline FVC (0.77, 0.58-1.04).Conclusion: In two large European studies, adults who reported more PA were at lower risk of developing a restrictive spirometry pattern. Lung function at baseline seemed to explain part of the observed association, stressing the need of adequate method to take into account both horse-racing and regression-to-the-means effects.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Keidel, DirkSwiss Trop & Publ Hlth Inst, Basel, Switzerland
(författare)
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Fuertes, ElaineCtr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
(författare)
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Imboden, MedeaSwiss Trop & Publ Hlth Inst, Basel, Switzerland
(författare)
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Weyler, JoostDept Epidemiol & Social Med, Antwerp, Belgium
(författare)
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Nowak, DennisUniv Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany
(författare)
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Heinrich, JoachimUniv Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany
(författare)
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Urrutia, IsabelGaldakao Hosp, Galdakao, Spain
(författare)
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Martinez-Moratalla, JoseComplejo Hosp Univ, Albacete, Spain
(författare)
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Caviezel, S.Swiss Trop & Publ Hlth Inst, Basel, Switzerland
(författare)
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Beckmeyer-Borowko, A.Swiss Trop & Publ Hlth Inst, Basel, Switzerland,Imperial Coll London, London, England
(författare)
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Raherison, ChantalBordeaux Univ, U1219, Bordeaux, France
(författare)
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Pin, IsabelleCHU Grenoble Alpes, Grenoble, France
(författare)
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Demoly, PascalUniv Hosp Montpellier, Hop Arnaud Villeneuve, Dept Pneumol & Addictol, Montpellier, France
(författare)
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Leynaert, BenedicteUniv Paris Diderot, INSERM, Equipe Epidemiol, UMR 1152, Paris, France
(författare)
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Cerveri, I.Univ Pavia, Pavia, Italy
(författare)
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Bono, RobertoUniv Turin, Dept Publ Hlth & Pediat, Turin, Italy
(författare)
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Accordini, SimoneUniv Verona, Dipartimento Diagnost & Sanita Pubbl, Verona, Italy
(författare)
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Amaral, A.
(författare)
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Gislason, ThorarigUniv Iceland, Reykjavik, Iceland
(författare)
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Svanes, CecilieUniv Bergen, Dept Clin Sci, Bergen, Norway
(författare)
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Toren, K.Univ Gothenburg, Gothenburg, Sweden
(författare)
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Forsberg, BertilUmeå universitet,Yrkes- och miljömedicin,Umea Univ, Div Occupat & Environm Med, Umea, Sweden(Swepub:umu)befo0001
(författare)
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Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)chrisjn
(författare)
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Dharmage, S.Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia
(författare)
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Jogi, RainTartu Univ Hosp, Lung Clin, Tartu, Estonia
(författare)
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Anto, JmCtr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
(författare)
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Probst-Hensch, NicoleSwiss Trop & Publ Hlth Inst, Basel, Switzerland
(författare)
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Garcia-Aymerich, JudithCtr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
(författare)
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Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, SpainSwiss Trop & Publ Hlth Inst, Basel, Switzerland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Respiratory Journal: European Respiratory Society520903-19361399-3003
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Carsin, Anne-Eli ...
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Keidel, Dirk
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Fuertes, Elaine
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Imboden, Medea
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Weyler, Joost
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Nowak, Dennis
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visa fler...
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Heinrich, Joachi ...
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Urrutia, Isabel
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Martinez-Moratal ...
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Caviezel, S.
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Beckmeyer-Borowk ...
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Raherison, Chant ...
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Pin, Isabelle
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Demoly, Pascal
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Leynaert, Benedi ...
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Cerveri, I.
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Bono, Roberto
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Accordini, Simon ...
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Amaral, A.
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Gislason, Thorar ...
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Svanes, Cecilie
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Toren, K.
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Forsberg, Bertil
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Janson, Christer
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Dharmage, S.
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Jogi, Rain
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Anto, Jm
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Probst-Hensch, N ...
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Garcia-Aymerich, ...
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