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Vitamin D status wa...
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Granlund, Lena E.,1960-Umeå universitet,Allmänmedicin
(författare)
Vitamin D status was not associated with anxiety, depression, or health-related quality of life in Middle Eastern and African-born immigrants in Sweden
- Artikel/kapitelEngelska2020
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Elsevier,2020
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LIBRIS-ID:oai:DiVA.org:umu-170510
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-170510URI
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https://doi.org/10.1016/j.nutres.2020.02.006DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Active vitamin D is a neurosteroid that may modulate brain function. Associations between vitamin D deficiency and depression and anxiety have been demonstrated. We hypothesized that there was an association between anxiety, depression, and health-related quality of life (HRQOL) and vitamin D status. To test this hypothesis, we examined the association between anxiety, depression, and HRQOL and 25-hydroxyvitamin D (25[OH]D) concentrations in the Middle Eastern and African-born immigrant population. All immigrants aged 25-65 years, born in 9 African or Middle Eastern countries, and living in 3 districts in Umea (n = 1306) were invited, with 195 English- or Swedish-speaking immigrants (104 men and 91 women) participated. Anxiety and depression were measured using the Hospital Anxiety and Depression scale. HRQOL was measured using EuroQoL-5 Dimension 3 Level Questionnaire and EuroQoL Visual Analogue Scale. Serum 25(OH)D was measured using liquid chromatography-tandem mass spectrometry. Associations were determined using logistic and linear regression. Analyses were adjusted for sex, age, origin, socioeconomic factors, lifestyle, chronic diseases, and obesity. In total, 71% had 25(OH)D less than 50 nmol/ L and 11% had 25(OH)D less than 25 nmol/L. Anxiety, depression, and HRQOL were not associated with 25(OH)D in the immigrant population. Anxiety was common in female immigrants from the Middle East (32.7%); and after adjustment, lower 25(OH)D concentrations were associated with higher risk of anxiety (25[OH]D <= 49 nmol/L vs 25[OH] D >= 50 nmol/L: odds ratio 23.2 [95% confidence interval 1.97 - 271.9] P = .012) in this subgroup only; however, reverse causality could not be excluded. In conclusion, the study showed no association between depression, anxiety, or HRQOL and vitamin D status in the immigrant population.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ramnemark, AnnaUmeå universitet,Geriatrik(Swepub:umu)anra0067
(författare)
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Andersson, ChristerUmeå universitet,Allmänmedicin(Swepub:umu)chan0003
(författare)
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Lindkvist, MarieUmeå universitet,Statistik,Institutionen för epidemiologi och global hälsa(Swepub:umu)mali0004
(författare)
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Norberg, MargaretaUmeå universitet,Institutionen för epidemiologi och global hälsa(Swepub:umu)mano0062
(författare)
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Fhärm, EvaUmeå universitet,Allmänmedicin(Swepub:umu)evfh0001
(författare)
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Umeå universitetAllmänmedicin
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Nutrition Research: Elsevier75, s. 109-1180271-53171879-0739
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