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Sökning: onr:"swepub:oai:DiVA.org:umu-177516" > Determinants of Ina...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005622naa a2200505 4500
001oai:DiVA.org:umu-177516
003SwePub
008201211s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1775162 URI
0247 a https://doi.org/10.3389/fpubh.2020.000902 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Afari-Asiedu, Samuelu Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
2451 0a Determinants of Inappropriate Antibiotics Use in Rural Central Ghana Using a Mixed Methods Approach
264 c 2020-03-24
264 1b Frontiers Media SA,c 2020
338 a electronic2 rdacarrier
520 a Background: The consequences of antibiotic resistance are projected to be most severe in low and middle income countries with high infectious disease burden. This study examined determinants of inappropriate antibiotic use at the community level in rural Ghana. Methods: An observational study involving qualitative and quantitative methods was conducted between July, 2016 and September, 2018 in Ghana. Two household surveys were conducted at two time points (2017 and 2018) among 1,100 randomly selected households over 1 year. The surveys focused on antibiotic use episodes in the past month. Four in-depth interviews and two focus group discussions were performed to further explain the survey results. Determinants of inappropriate antibiotic use were assessed using a mixed effect logistic regression analysis (multilevel analysis) to account for the clustered nature of data. We defined inappropriate antibiotic use as either use without prescription, not completing treatment course or non-adherence to instruction for use. Qualitative data were thematically analyzed. Results: A total of 1,100 households was enrolled in which antibiotics were used in 585 (53.2%) households in the month prior to the surveys. A total of 676 (21.2%) participants out of 3,193 members from the 585 reportedly used antibiotics for 761 episodes of illness. Out of the 761 antibiotic use episodes, 659 (86.6%) were used inappropriately. Paying for healthcare without health insurance (Odds Ratio (OR): 2.10, 95% CI: 1.1-7.4, p-value: 0.026), not seeking healthcare from health centers (OR: 2.4, 95% CI: 1.2-5.0, p-value: 0.018), or pharmacies (OR: 4.6, 95% CI: 1.7-13.0, p-value: 0.003) were significantly associated with inappropriate antibiotic use. Socio-demographic characteristics were not significantly associated with inappropriate antibiotic use. However, the qualitative study described the influence of cost of medicines on inappropriate antibiotic use. It also revealed that antibiotic users with low socioeconomic status purchased antibiotics in installments which, could facilitate inappropriate use. Conclusion: Inappropriate antibiotic use was high and influenced by out-of-pocket payment for healthcare, seeking healthcare outside health centers, pharmacies, and buying antibiotics in installments due to cost. To improve appropriate antibiotic use, there is the need for ministry of health and healthcare agencies in Ghana to enhance healthcare access and healthcare insurance, and to provide affordable antibiotics.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
653 a Ghana
653 a antibiotic resistance
653 a antibiotic use
653 a antibiotics
653 a inappropriate antibiotic use
7001 a Oppong, Felix Boakyeu Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7001 a Tostmann, Almau Radboud University Medical Center, Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Ali Abdulai, Marthau Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7001 a Boamah-Kaali, Ellenu Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7001 a Gyaase, Stephaneyu Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7001 a Agyei, Oscaru Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7001 a Kinsman, Johnu Umeå universitet,Institutionen för epidemiologi och global hälsa4 aut0 (Swepub:umu)joki0020
7001 a Hulscher, Marliesu Radboud University Medical Center, Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Wertheim, Heiman F. L.u Radboud University Medical Center, Institute for Health Sciences, Nijmegen, Netherlands4 aut
7001 a Asante, Kwaku Pokuu Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana4 aut
7102 a Kintampo Health Research Centre, Ghana Health Service, Kintampo, Ghanab Radboud University Medical Center, Institute for Health Sciences, Nijmegen, Netherlands4 org
7730 t Frontiers In Public Healthd : Frontiers Media SAg 8q 8x 2296-2565
8564 u https://doi.org/10.3389/fpubh.2020.00090y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1508935/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://www.frontiersin.org/articles/10.3389/fpubh.2020.00090/pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177516
8564 8u https://doi.org/10.3389/fpubh.2020.00090

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