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Sökning: onr:"swepub:oai:DiVA.org:umu-178366" > Daily step count an...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004619naa a2200481 4500
001oai:DiVA.org:umu-178366
003SwePub
008210112s2020 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1783662 URI
024a https://doi.org/10.1186/s12889-020-09929-22 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Ballin, Marcelu Umeå universitet,Geriatrik,Avdelningen för hållbar hälsa4 aut0 (Swepub:umu)maba0220
2451 0a Daily step count and incident diabetes in community-dwelling 70-year-olds :b a prospective cohort study
264 c 2020-11-30
264 1b BioMed Central,c 2020
338 a electronic2 rdacarrier
520 a Background: Older adults with diabetes take fewer steps per day than those without diabetes. The purpose of the present study was to investigate the association of daily step count with incident diabetes in community-dwelling 70-year-olds.Methods: This prospective cohort study included N = 3055 community-dwelling 70-year-olds (52% women) who participated in a health examination in Umeå, Sweden during 2012–2017, and who were free from diabetes at baseline. Daily step count was measured for 1 week using Actigraph GT3X+ accelerometers. Cases of diabetes were collected from the Swedish National Patient Register. The dose-response association was evaluated graphically using a flexible parametric model, and hazard ratios (HR) with 95% confidence intervals (CI) were calculated using Cox regressions.Results: During a mean follow-up of 2.6 years, diabetes was diagnosed in 81 participants. There was an inverse nonlinear dose-response association between daily step count and incident diabetes, with a steep decline in risk of diabetes from a higher daily step count until around 6000 steps/day. From there, the risk decreased at a slower rate until it leveled off at around 8000 steps/day. A threshold of 4500 steps/day was found to best distinguish participants with the lowest risk of diabetes, where those taking ≥ 4500 steps/day, had 59% lower risk of diabetes, compared to those taking fewer steps (HR, 0.41, 95% CI, 0.25–0.66). Adjusting for visceral adipose tissue (VAT) attenuated the association (HR, 0.64, 95% CI, 0.38–1.06), which was marginally altered after further adjusting for sedentary time, education and other cardiometabolic risk factors and diseases (HR, 0.58, 95% CI, 0.32–1.05).Conclusions: A higher daily step count is associated with lower risk of incident diabetes in community-dwelling 70-year-olds. The greatest benefits occur at the lower end of the activity range, and much earlier than 10,000 steps/day. With the limitation of being an observational study, these findings suggest that promoting even a modest increase in daily step count may help to reduce the risk of diabetes in older adults. Because VAT appears to partly mediate the association, lifestyle interventions targeting diabetes should apart from promoting physical activity also aim to prevent and reduce central obesity.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng
653 a Physical activity
653 a Walking
653 a Accelerometry
653 a Metabolic syndrome
653 a Non-communicable disease
653 a Visceral adipose tissue
653 a Obesity
700a Nordström, Peteru Umeå universitet,Geriatrik4 aut0 (Swepub:umu)peno0014
700a Niklasson, Johanu Umeå universitet,Geriatrik4 aut0 (Swepub:umu)joni0103
700a Alamäki, Antti4 aut
700a Condell, Joan4 aut
700a Tedesco, Salvatore4 aut
700a Nordström, Annau Umeå universitet,Avdelningen för hållbar hälsa,School of Sport Sciences, UiT the Arctic University of Norway, Tromsø, Norway4 aut0 (Swepub:umu)anagun97
710a Umeå universitetb Geriatrik4 org
773t BMC Public Healthd : BioMed Centralg 20:1q 20:1x 1471-2458
856u https://doi.org/10.1186/s12889-020-09929-2y Fulltext
856u https://umu.diva-portal.org/smash/get/diva2:1516557/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u https://bmcpublichealth.biomedcentral.com/track/pdf/10.1186/s12889-020-09929-2
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-178366
8564 8u https://doi.org/10.1186/s12889-020-09929-2

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