Sökning: onr:"swepub:oai:DiVA.org:umu-181996" > The Functional Foun...
Fältnamn | Indikatorer | Metadata |
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000 | 04851naa a2200493 4500 | |
001 | oai:DiVA.org:umu-181996 | |
003 | SwePub | |
008 | 210412s2021 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1819962 URI |
024 | 7 | a https://doi.org/10.1093/cercor/bhaa3482 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Vidal-Piñeiro, Didacu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
245 | 1 0 | a The Functional Foundations of Episodic Memory Remain Stable Throughout the Lifespan |
264 | c 2020-11-30 | |
264 | 1 | b Oxford University Press,c 2021 |
338 | a electronic2 rdacarrier | |
520 | a It has been suggested that specific forms of cognition in older age rely largely on late-life specific mechanisms. Here instead, we tested using task-fMRI (n = 540, age 6-82 years) whether the functional foundations of successful episodic memory encoding adhere to a principle of lifespan continuity, shaped by developmental, structural, and evolutionary influences. We clustered regions of the cerebral cortex according to the shape of the lifespan trajectory of memory activity in each region so that regions showing the same pattern were clustered together. The results revealed that lifespan trajectories of memory encoding function showed a continuity through life but no evidence of age-specific mechanisms such as compensatory patterns. Encoding activity was related to general cognitive abilities and variations of grey matter as captured by a multi-modal independent component analysis, variables reflecting core aspects of cognitive and structural change throughout the lifespan. Furthermore, memory encoding activity aligned to fundamental aspects of brain organization, such as large-scale connectivity and evolutionary cortical expansion gradients. Altogether, we provide novel support for a perspective on memory aging in which maintenance and decay of episodic memory in older age needs to be understood from a comprehensive life-long perspective rather than as a late-life phenomenon only. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng |
653 | a aging | |
653 | a development | |
653 | a encoding | |
653 | a fMRI | |
653 | a neuroimaging | |
700 | 1 | a Sneve, Markus H.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Amlien, Inge K.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Grydeland, Håkonu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Mowinckel, Athanasia M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Roe, James M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Sørensen, Øysteinu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Nyberg, Lars H.,d 1966-u Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Fysiologi,Diagnostisk radiologi4 aut0 (Swepub:umu)lany0001 |
700 | 1 | a Walhovd, Kristine B.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway4 aut |
700 | 1 | a Fjell, Anders M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway4 aut |
710 | 2 | a Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norwayb Umeå centrum för funktionell hjärnavbildning (UFBI)4 org |
773 | 0 | t Cerebral Cortexd : Oxford University Pressg 31:4, s. 2098-2110q 31:4<2098-2110x 1047-3211x 1460-2199 |
856 | 4 | u https://doi.org/10.1093/cercor/bhaa348y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1543667/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://academic.oup.com/cercor/article-pdf/31/4/2098/36458471/bhaa348.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181996 |
856 | 4 8 | u https://doi.org/10.1093/cercor/bhaa348 |
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