Sökning: onr:"swepub:oai:DiVA.org:umu-184123" >
MAP2K1-Mutated Mela...
MAP2K1-Mutated Melanocytic Neoplasms With a SPARK-Like Morphology
-
- Donati, Michele (författare)
- Department of Pathology, University Hospital Campus Bio-Medico, Rome, Italy; Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic
-
- Nosek, Daniel (författare)
- Umeå universitet,Patologi
-
- Waldenbäck, Pia (författare)
- Umeå universitet,Patologi
-
visa fler...
-
- Martinek, Petr (författare)
- Bioptical Laboratory, Pilsen, Czech Republic
-
- Jonsson, Björn-Anders (författare)
- Umeå universitet,Patologi
-
- Galgonkova, Petra (författare)
- Department of Pathology, Regional Hospital, Czech Republic
-
- Hawawrehova, Marcela (författare)
- Department of Pathology, NEMOS Hospital, Sokolov, Czech Republic
-
- Berouskova, Petra (författare)
- Department of Pathology, Regional Hospital, Kladno, Czech Republic; and
-
- Kastnerova, Liubov (författare)
- Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic; Bioptical Laboratory, Pilsen, Czech Republic
-
- Persichetti, Paolo (författare)
- Department of Pathology, Regional Hospital, Kladno, Czech Republic; and
-
- Crescenzi, Anna (författare)
- Department of Pathology, University Hospital Campus Bio-Medico, Rome, Italy
-
- Michal, Michal (författare)
- Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic; Bioptical Laboratory, Pilsen, Czech Republic
-
- Kazakov, Dmitry V. (författare)
- Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic; Bioptical Laboratory, Pilsen, Czech Republic
-
visa färre...
-
(creator_code:org_t)
- Wolters Kluwer, 2021
- 2021
- Engelska.
-
Ingår i: American journal of dermatopathology. - : Wolters Kluwer. - 0193-1091 .- 1533-0311. ; 43:6, s. 412-417
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Specific alterations involving MAPK genes (MAP3K8 fusions, MAP3K3 fusions) have been recently detected in a subgroup of spitzoid neoplasms that seem to constitute a distinctive clinicopathologic group, occur mostly in younger patients (median age 18 years) and present with atypical histologic features associated with frequent homozygous deletion of CDKN2A, qualifying a high proportion of them as Spitz melanoma (malignant Spitz tumor). Apart from lesions with spitzoid morphology harboring MAP3K8 or MAP3K3 fusion, a single case with MAP2K1 deletion has been identified. The authors report herein 4 melanocytic lesions with a MAP2K1 mutation, all showing similar microscopic appearances, including spitzoid cytology and dysplastic architectural features, resembling so-called SPARK nevus, suggesting that these lesions may represent another distinctive group.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Donati, Michele
-
Nosek, Daniel
-
Waldenbäck, Pia
-
Martinek, Petr
-
Jonsson, Björn-A ...
-
Galgonkova, Petr ...
-
visa fler...
-
Hawawrehova, Mar ...
-
Berouskova, Petr ...
-
Kastnerova, Liub ...
-
Persichetti, Pao ...
-
Crescenzi, Anna
-
Michal, Michal
-
Kazakov, Dmitry ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Medicinska och f ...
-
och Medicinsk geneti ...
- Artiklar i publikationen
-
American journal ...
- Av lärosätet
-
Umeå universitet