Sökning: onr:"swepub:oai:DiVA.org:umu-184127" >
Biological Effect o...
Biological Effect of Silver-modified Nanostructured Titanium Dioxide in Cancer
-
- Lagopati, Nefeli (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Laboratory of General Chemistry, School of Chemical Engineering, National Technical University of Athens, Zografou Campus, Athens, Greece; Biomedical Research Foundation Academy of Athens, Athens, Greece
-
- Kotsinas, Athanassios (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece
-
- Veroutis, Dimitris (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Biomedical Research Foundation Academy of Athens, Athens, Greece
-
visa fler...
-
- Evangelou, Konstantinos (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece
-
- Papaspyropoulos, Angelos (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Biomedical Research Foundation Academy of Athens, Athens, Greece
-
- Arfanis, Michalis (författare)
- Institute of Nanoscience and Nanotechnology, Laboratory of Nanotechnology Processes for Solar Energy Conversion and Environmental Protection, National Centre for Scientific Research "Demokritos", Athens, Greece
-
- Falaras, Polycarpos (författare)
- Institute of Nanoscience and Nanotechnology, Laboratory of Nanotechnology Processes for Solar Energy Conversion and Environmental Protection, National Centre for Scientific Research "Demokritos", Athens, Greece
-
- Kitsiou, Paraskevi V. (författare)
- Institute of Biosciences and Applications, Laboratory of Biochemistry/Cell & Matrix Pathobiology, National Centre for Scientific Research "Demokritos", Athens, Greece
-
- Pateras, Ioannis (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece
-
- Bergonzini, Anna (författare)
- Umeå universitet,Umeå Centre for Microbial Research (UCMR),Institutionen för molekylärbiologi (Medicinska fakulteten),Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet)
-
- Frisan, Teresa, 1967- (författare)
- Umeå universitet,Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet),Umeå Centre for Microbial Research (UCMR)
-
- Kyriazis, Spyridon (författare)
- Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece
-
- Tsoukleris, Dimitrios S. (författare)
- Laboratory of General Chemistry, School of Chemical Engineering, National Technical University of Athens, Zografou Campus, Athens, Greece; NanoViis Company, Athens, Greece
-
- Tsilibary, Effie-Photini C (författare)
- Department of Neuroscience, University of Minnesota, MN, Minneapolis, United States
-
- Gazouli, Maria (författare)
- Department of Basic Medical Sciences, Laboratory of Biology, Faculty of Medicine, School of Health Science, National and Kapodistrian University of Athens, Athens, Greece
-
- Pavlatou, Evangelia A. (författare)
- Laboratory of General Chemistry, School of Chemical Engineering, National Technical University of Athens, Zografou Campus, Athens, Greece; vgorg@med.uoa.gr pavlatou@chemeng.ntua.gr
-
- Gorgoulis, Vassilis G. (författare)
- Biomedical Research Foundation Academy of Athens, Athens, Greece; Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece; vgorg@med.uoa.gr pavlatou@chemeng.ntua.gr; Faculty of Biology, Medicine and Health Manchester Cancer Research Centre, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom; Center for New Biotechnologies and Precision Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece
-
visa färre...
-
(creator_code:org_t)
- 2021-05-15
- 2021
- Engelska.
-
Ingår i: Cancer Genomics & Proteomics. - : Anticancer Research USA Inc.. - 1109-6535 .- 1790-6245. ; 18:3, s. 425-439
- Relaterad länk:
-
https://cgp.iiarjour...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.2...
-
visa färre...
Abstract
Ämnesord
Stäng
- BACKGROUND/AIM: Nanomedicine is a promising scientific field that exploits the unique properties of innovative nanomaterials, providing alternative solutions in diagnostics, prevention and therapeutics. Titanium dioxide nanoparticles (TiO2 NPs) have a great spectrum of photocatalytic antibacterial and anticancer applications. The chemical modification of TiO2 optimizes its bioactive performance. The aim of this study was the development of silver modified NPs (Ag/TiO2 NPs) with anticancer potential.MATERIALS AND METHODS: Ag/TiO2 NPs were prepared through the sol-gel method, were fully characterized and were tested on cultured breast cancer epithelial cells (MCF-7 and MDA-MB-231). The MTT colorimetric assay was used to estimate cellular viability. Western blot analysis of protein expression along with a DNA-laddering assay were employed for apoptosis detection.RESULTS AND CONCLUSION: We show that photo-activated Ag/TiO2 NPs exhibited significant cytotoxicity on the highly malignant MDA-MB-231 cancer cells, inducing apoptosis, while MCF-7 cells that are characterized by low invasive properties were unaffected under the same conditions.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- anticancer properties
- apoptosis
- cytotoxicity
- Nanomedicine
- nanostructured titanium dioxide
- photocatalysis
- silver-modified titanium dioxide
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Lagopati, Nefeli
-
Kotsinas, Athana ...
-
Veroutis, Dimitr ...
-
Evangelou, Konst ...
-
Papaspyropoulos, ...
-
Arfanis, Michali ...
-
visa fler...
-
Falaras, Polycar ...
-
Kitsiou, Paraske ...
-
Pateras, Ioannis
-
Bergonzini, Anna
-
Frisan, Teresa, ...
-
Kyriazis, Spyrid ...
-
Tsoukleris, Dimi ...
-
Tsilibary, Effie ...
-
Gazouli, Maria
-
Pavlatou, Evange ...
-
Gorgoulis, Vassi ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
- Artiklar i publikationen
-
Cancer Genomics ...
- Av lärosätet
-
Umeå universitet