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Aortic valve stenos...
Aortic valve stenosis and cardiac amyloidosis : A misleading association
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- Bonelli, Andrea (författare)
- Cardiology Unit, Spedali Civili and University of Brescia, Brescia, Italy
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- Paris, Sara (författare)
- Cardiology Unit, Spedali Civili and University of Brescia, Brescia, Italy
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- Nardi, Matilde (författare)
- Cardiology Unit, Spedali Civili and University of Brescia, Brescia, Italy
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- Henein, Michael Y. (författare)
- Umeå universitet,Avdelningen för medicin
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- Agricola, Eustachio (författare)
- Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, San Raffaele Hospital, Vita-Salute University, Milan, Italy
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- Troise, Giovanni (författare)
- Cardiac Surgery, Cardiothoracic Department, Fondazione Poliambulanza, Brescia, Italy
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- Faggiano, Pompilio (författare)
- Cardiology, Cardiothoracic Department, Fondazione Poliambulanza, Brescia, Italy
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(creator_code:org_t)
- 2021-09-18
- 2021
- Engelska.
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Ingår i: Journal of Clinical Medicine. - : MDPI. - 2077-0383. ; 10:18
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- The association between aortic stenosis (AS) and cardiac amyloidosis (CA) is more frequent than expected. Albeit rare, CA, particularly the transthyretin (ATTR) form, is commonly found in elderly people. ATTR-CA is also the most prevalent form in patients with AS. These conditions share pathophysiological, clinical and imaging findings, making the diagnostic process very challenging. To date, a multiparametric evaluation is suggested in order to detect patients with both AS and CA and choose the best therapeutic option. Given the accuracy of modern non-invasive techniques (i.e., bone scintigraphy), early diagnosis of CA is possible. Flow-charts with the main CA findings which may help clinicians in the diagnostic process have been proposed. The prognostic impact of the combination of AS and CA is not fully known; however, new available specific treatments of ATTR-CA have changed the natural history of the disease and have some impact on the decision-making process for the management of AS. Hence the relevance of detecting these two conditions when simultaneously present. The specific features helping the detection of AS-CA association are discussed in this review, focusing on the shared pathophysiological characteristics and the common clinical and imaging hallmarks.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Amyloidosis
- Aortic valve stenosis
- Multimodality imaging
- Transthyretin amyloidosis
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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