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Prostate tissue sti...
Prostate tissue stiffness as measured with a resonance sensor system : a study on silicone and human prostate tissue in vitro.
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- Jalkanen, Ville, 1978- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University. Department of Applied Physics and Electronics
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- Andersson, Britt M, 1962- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University. Department of Applied Physics and Electronics
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- Bergh, Anders (författare)
- Umeå universitet,Institutionen för medicinsk biovetenskap,Umeå University, Department of Medical Biosciences, Pathology
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- Ljungberg, Börje (författare)
- Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå University, Department of Surgical and Perioperative Science, Urology and Andrology
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- Lindahl, Olof A (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF)
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(creator_code:org_t)
- 2006-06-10
- 2006
- Engelska.
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Ingår i: Medical and Biological Engineering and Computing. - : Springer Science and Business Media LLC. - 0140-0118 .- 1741-0444. ; 44:7, s. 593-603
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Prostate cancer is the most common form of cancer in men in Europe and in the USA. Some prostate tumours are stiffer than the surrounding normal tissue, and it could therefore be of interest to measure prostate tissue stiffness. Resonance sensor technology based on piezoelectric resonance detects variations in tissue stiffness due to a change in the resonance frequency. An impression-controlled resonance sensor system was used to detect stiffness in silicone rubber and in human prostate tissue in vitro using two parameters, both combinations of frequency change and force. Variations in silicone rubber stiffness due to the mixing ratio of the two components could be detected (p<0.05) using both parameters. Measurements on prostate tissue showed that there existed a statistically significant (MANOVA test, p<0.001) reproducible difference between tumour tissue (n=13) and normal healthy tissue (n=98) when studying a multivariate parameter set. Both the tumour tissue and normal tissue groups had variations within them, which were assumed to be related to differences in tissue composition. Other sources of error could be uneven surfaces and different levels of dehydration for the prostates. Our results indicated that the resonance sensor could be used to detect stiffness variations in silicone and in human prostate tissue in vitro. This is promising for the development of a future diagnostic tool for prostate cancer.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
Nyckelord
- prostate tissue
- stiffness
- resonance sensor
- Medical engineering
- Medicinsk teknik
- Medical Engineering for Healthcare
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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