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Evaluation of appla...
Evaluation of applanation resonator sensors for intra-ocular pressure measurement : results from clinical and in vitro studies.
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- Eklund, Anders (författare)
- Umeå universitet,Radiofysik,Umeå University Hospital, Department of Biomedical Engineering & Informatics
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- Lindén, Christina (författare)
- Umeå universitet,Institutionen för klinisk vetenskap,Umeå University, Department of Clinical Science, Ophthalmology
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- Bäcklund, Tomas (författare)
- Umeå universitet,Radiofysik,Umeå University Hospital, Department of Biomedical Engineering & Informatics
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- Andersson, Britt M, 1962- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF),Umeå University. Department of Applied Physics and Electronics
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- Lindahl, Olof A, 1955- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF)
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(creator_code:org_t)
- 2003
- 2003
- Engelska.
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Ingår i: Medical and Biological Engineering and Computing. - 0140-0118 .- 1741-0444. ; 41:2, s. 190-197
- Relaterad länk:
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Glaucoma is an eye disease that, in its most common form, is characterised by high intra-ocular pressure (IOP), reduced visual field and optic nerve damage. For diagnostic purposes and for follow-up after treatment, it is important to have simple and reliable methods for measuring IOP. Recently, an applanation resonator sensor (ARS) for measuring IOP was introduced and evaluated using an in vitro pig-eye model. In the present study, the first clinical evaluation of the same probe has been carried out, with experiments in vivo on human eyes. There was a low but significant correlation between IOP(ARS) and the IOP measured with a Goldmann applanation tonometer (r = 0.40, p = 0.001, n = 72). However, off-centre positioning of the sensor against the cornea caused a non-negligible source of error. The sensor probe was redesigned to have a spherical, instead of flat, contact surface against the eye and was evaluated in the in vitro model. The new probe showed reduced sensitivity to off-centre positioning, with a decrease in relative deviation from 89% to 11% (1 mm radius). For normalised data, linear regression between IOP(ARS) and direct IOP measurement in the vitreous chamber showed a correlation of r = 0.97 (p < 0.001, n = 108) and a standard deviation for the residuals of SD < or = 2.18 mm Hg (n = 108). It was concluded that a spherical contact surface should be preferred and that further development towards a clinical instrument should focus on probe design and signal analysis.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oftalmologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Ophthalmology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
Nyckelord
- resonance sensor
- intra-ocular pressure
- Medical engineering
- Medicinsk teknik
- Ophtalmiatrics
- Oftalmiatrik
- Ophtalmology
- oftalmiatrik
- Medical Engineering for Healthcare
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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