Sökning: onr:"swepub:oai:DiVA.org:umu-193275" > Development, valida...
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000 | 06130naa a2201057 4500 | |
001 | oai:DiVA.org:umu-193275 | |
003 | SwePub | |
008 | 220324s2021 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:146377687 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1932752 URI |
024 | 7 | a https://doi.org/10.1002/jhbp.9622 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1463776872 URI |
040 | a (SwePub)umud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kim, Hyeong Seok4 aut |
245 | 1 0 | a Development, validation, and comparison of a nomogram based on radiologic findings for predicting malignancy in intraductal papillary mucinous neoplasms of the pancreas :b An international multicenter study |
264 | c 2021 | |
264 | 1 | b Wiley-Blackwell,c 2021 |
338 | a print2 rdacarrier | |
520 | a BACKGROUND: Although we previously proposed a nomogram to predict malignancy in intraductal papillary mucinous neoplasms (IPMN) and validated it in an external cohort, its application is challenging without data on tumor markers. Moreover, existing nomograms have not been compared. This study aimed to develop a nomogram based on radiologic findings and to compare its performance with previously proposed American and Korean/Japanese nomograms.METHODS: We recruited 3708 patients who underwent surgical resection at 31 tertiary institutions in eight countries, and patients with main pancreatic duct >10 mm were excluded. To construct the nomogram, 2606 patients were randomly allocated 1:1 into training and internal validation sets, and area under the receiver operating characteristics curve (AUC) was calculated using 10-fold cross validation by exhaustive search. This nomogram was then validated and compared to the American and Korean/Japanese nomograms using 1102 patients.RESULTS: Among the 2606 patients, 90 had main-duct type, 900 had branch-duct type, and 1616 had mixed-type IPMN. Pathologic results revealed 1628 low-grade dysplasia, 476 high-grade dysplasia, and 502 invasive carcinoma. Location, cyst size, duct dilatation, and mural nodule were selected to construct the nomogram. AUC of this nomogram was higher than the American nomogram (0.691 vs 0.664, P = .014) and comparable with the Korean/Japanese nomogram (0.659 vs 0.653, P = .255).CONCLUSIONS: A novel nomogram based on radiologic findings of IPMN is competitive for predicting risk of malignancy. This nomogram would be clinically helpful in circumstances where tumor markers are not available. The nomogram is freely available at http://statgen.snu.ac.kr/software/nomogramIPMN. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
653 | a cancer | |
653 | a intraductal papillary mucinous neoplasms of the pancreas | |
653 | a malignancy prediction | |
653 | a nomogram | |
653 | a radiology | |
700 | 1 | a Song, Wookyeong4 aut |
700 | 1 | a Choo, Wonho4 aut |
700 | 1 | a Lee, Sungyoung4 aut |
700 | 1 | a Han, Youngmin4 aut |
700 | 1 | a Bassi, Claudio4 aut |
700 | 1 | a Salvia, Roberto4 aut |
700 | 1 | a Marchegiani, Giovanni4 aut |
700 | 1 | a Wolfgang, Christopher L.4 aut |
700 | 1 | a He, Jin4 aut |
700 | 1 | a Blair, Alex B.4 aut |
700 | 1 | a Kluger, Michael D.4 aut |
700 | 1 | a Su, Gloria H.4 aut |
700 | 1 | a Kim, Song Cheol4 aut |
700 | 1 | a Song, Ki-Byung4 aut |
700 | 1 | a Yamamoto, Masakazu4 aut |
700 | 1 | a Hatori, Takashi4 aut |
700 | 1 | a Yang, Ching-Yao4 aut |
700 | 1 | a Yamaue, Hiroki4 aut |
700 | 1 | a Hirono, Seiko4 aut |
700 | 1 | a Satoi, Sohei4 aut |
700 | 1 | a Fujii, Tsutomu4 aut |
700 | 1 | a Hirano, Satoshi4 aut |
700 | 1 | a Lou, Wenhui4 aut |
700 | 1 | a Hashimoto, Yasushi4 aut |
700 | 1 | a Shimizu, Yasuhiro4 aut |
700 | 1 | a Del Chiaro, Marco4 aut |
700 | 1 | a Valente, Robertou Pancreatic Surgery Unit, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute at Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Digestive and Liver Disease Unit, Sapienza University of Rome, Rome, Italy4 aut0 (Swepub:umu)rova0033 |
700 | 1 | a Lohr, Matthiasu Karolinska Institutet4 aut |
700 | 1 | a Choi, Dong Wook4 aut |
700 | 1 | a Choi, Seong Ho4 aut |
700 | 1 | a Heo, Jin Seok4 aut |
700 | 1 | a Motoi, Fuyuhiko4 aut |
700 | 1 | a Matsumoto, Ippei4 aut |
700 | 1 | a Lee, Woo Jung4 aut |
700 | 1 | a Kang, Chang Moo4 aut |
700 | 1 | a Shyr, Yi-Ming4 aut |
700 | 1 | a Wang, Shin-E4 aut |
700 | 1 | a Han, Ho-Seong4 aut |
700 | 1 | a Yoon, Yoo-Seok4 aut |
700 | 1 | a Besselink, Marc G.4 aut |
700 | 1 | a van Huijgevoort, Nadine C. M.4 aut |
700 | 1 | a Sho, Masayuki4 aut |
700 | 1 | a Nagano, Hiroaki4 aut |
700 | 1 | a Kim, Sang Geol4 aut |
700 | 1 | a Honda, Goro4 aut |
700 | 1 | a Yang, Yinmo4 aut |
700 | 1 | a Yu, Hee Chul4 aut |
700 | 1 | a Yang, Jae Do4 aut |
700 | 1 | a Chung, Jun Chul4 aut |
700 | 1 | a Nagakawa, Yuichi4 aut |
700 | 1 | a Seo, Hyung Il4 aut |
700 | 1 | a Lee, Seungyeoun4 aut |
700 | 1 | a Kim, Hongbeom4 aut |
700 | 1 | a Kwon, Wooil4 aut |
700 | 1 | a Park, Taesung4 aut |
700 | 1 | a Jang, Jin-Young4 aut |
710 | 2 | a Karolinska Institutetb Pancreatic Surgery Unit, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute at Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Digestive and Liver Disease Unit, Sapienza University of Rome, Rome, Italy4 org |
773 | 0 | t Journal of hepato-biliary-pancreatic sciencesd : Wiley-Blackwellx 1868-6974x 1868-6982 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-193275 |
856 | 4 8 | u https://doi.org/10.1002/jhbp.962 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:146377687 |
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