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Optimizing social and economic activity while containing SARS-CoV-2 transmission using DAEDALUS

Haw, David J. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Forchini, Giovanni (författare)
Umeå universitet,Nationalekonomi,MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Doohan, Patrick (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
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Christen, Paula (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Pianella, Matteo (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Johnson, Robert (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Bajaj, Sumali (författare)
Department of Zoology, University of Oxford, Oxford, United Kingdom
Hogan, Alexandra B. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom; School of Population Health, University of New South Wales, Sydney, Australia
Winskill, Peter (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Miraldo, Marisa (författare)
Department of Economics and Public Policy, Imperial College Business School, London, United Kingdom
White, Peter J. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom; Modelling and Economics Unit, UK Health Security Agency, London, United Kingdom
Ghani, Azra C. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Ferguson, Neil M. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
Smith, Peter C. (författare)
Department of Economics and Public Policy, Imperial College Business School, London, United Kingdom; Centre for Health Economics, University of York, York, United Kingdom
Hauck, Katharina D. (författare)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute, Imperial College London, London, United Kingdom
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 (creator_code:org_t)
2022-04-28
2022
Engelska.
Ingår i: Nature Computational Science. - : Springer Science and Business Media LLC. - 2662-8457. ; 2:4, s. 223-233
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • To study the trade-off between economic, social and health outcomes in the management of a pandemic, DAEDALUS integrates a dynamic epidemiological model of SARS-CoV-2 transmission with a multi-sector economic model, reflecting sectoral heterogeneity in transmission and complex supply chains. The model identifies mitigation strategies that optimize economic production while constraining infections so that hospital capacity is not exceeded but allowing essential services, including much of the education sector, to remain active. The model differentiates closures by economic sector, keeping those sectors open that contribute little to transmission but much to economic output and those that produce essential services as intermediate or final consumption products. In an illustrative application to 63 sectors in the United Kingdom, the model achieves an economic gain of between £161 billion (24%) and £193 billion (29%) compared to a blanket lockdown of non-essential activities over six months. Although it has been designed for SARS-CoV-2, DAEDALUS is sufficiently flexible to be applicable to pandemics with different epidemiological characteristics.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

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