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Step-by-step diagno...
Step-by-step diagnosis and management of the nocebo/drucebo effect in statin-associated muscle symptoms patients : a position paper from the International Lipid Expert Panel (ILEP)
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- Penson, Peter E. (författare)
- School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, United Kingdom; Liverpool Centre for Cardiovascular Science, Liverpool, United Kingdom
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- Bruckert, Eric (författare)
- Pitié-Salpetrière Hospital and Sorbonne University, Cardio metabolic Institute, Paris, France
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- Marais, David (författare)
- Chemical Pathology Division of the Department of Pathology, University of Cape Town Health Science Faculty, Cape Town, South Africa
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- Reiner, Željko (författare)
- Department of Internal Medicine, University Hospital Centre Zagreb, School of Medicine University of Zagreb, Zagreb, Croatia
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- Pirro, Matteo (författare)
- Department of Medicine, University of Perugia, Perugia, Italy
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- Sahebkar, Amirhossein (författare)
- Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Clinic of Cardiology, University Clinical Centre of Kosova, Medical Faculty, University of Prishtina, Prishtina,Kosovo
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- Bajraktari, Gani (författare)
- Umeå universitet,Avdelningen för medicin,Department of Internal Disease, Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan
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- Mirrakhimov, Erkin (författare)
- Department of Atherosclerosis and Coronary Heart Disease, National Center of Cardiology and Internal Diseases, Bishkek, Kyrgyzstan
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- Rizzo, Manfredi (författare)
- Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy; Division of Endocrinology, Diabetes and Metabolism, School of Medicine, University of South Carolina, SC, Columbia, United States
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- Mikhailidis, Dimitri P. (författare)
- Department of Clinical Biochemistry, University College London Medical School, University College London (UCL), London, United Kingdom
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- Sachinidis, Alexandros (författare)
- Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy; 2nd Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
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- Gaita, Dan (författare)
- Universitatea de Medicina si Farmacie Victor Babes, Timisoara, Romania; Clinica de Cardiologie, Institutul de Boli Cardiovasculare Timisoara, Timisoara, Romania
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- Latkovskis, Gustavs (författare)
- Pauls Stradins Clinical University Hospital, Riga, Latvia; University of Latvia, Riga, Latvia
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- Mazidi, Mohsen (författare)
- Medical Research Council Population Health Research Unit, University of Oxford, Oxford, United Kingdom; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
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- Toth, Peter P. (författare)
- CGH Medical Center, IL, Sterling, United States; Cicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, MD, Baltimore, United States
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- Pella, Daniel (författare)
- 2nd Department of Cardiology of the East Slovak Institute of Cardiovascular Disease and Faculty of Medicine, PJ Safarik University, Kosice, Slovakia
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- Alnouri, Fahad (författare)
- Cardiovascular Prevention Unit, Adult Cardiology Department, Prince Sultan Cardiac Centre Riyadh, Riyadh, Saudi Arabia
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- Postadzhiyan, Arman (författare)
- Department of General Medicine, Emergency University Hospital ‘St. Anna’, Medical University of Sofia, Sofia, Bulgaria
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- Yeh, Hung-I (författare)
- Department of Medicine, MacKay Medical College, New Taipei City, Taiwan
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- Mancini, G.B. John (författare)
- Department of General Medicine, Emergency University Hospital ‘St. Anna’, Medical University of Sofia, Sofia, Bulgaria
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- von Haehling, Stephan (författare)
- Department of Cardiology and Pneumology, Heart Center, University of Göttingen Medical Center, Göttingen, Germany; German Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany
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- Banach, Maciej (författare)
- Polish Moother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland; Department of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Zielona Gora, Poland
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(creator_code:org_t)
- 2022-03-10
- 2022
- Engelska.
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Ingår i: Journal of Cachexia, Sarcopenia and Muscle. - : John Wiley & Sons. - 2190-5991 .- 2190-6009. ; 13:3, s. 1596-1622
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with statin therapy [most commonly statin-associated muscle symptoms (SAMS)] result in the discontinuation of therapy and consequently increase the risk of adverse cardiovascular outcomes. However, complete statin intolerance occurs in only a small minority of treated patients (estimated prevalence of only 3–5%). Many perceived AEs are misattributed (e.g. physical musculoskeletal injury and inflammatory myopathies), and subjective symptoms occur as a result of the fact that patients expect them to do so when taking medicines (the nocebo/drucebo effect)—what might be truth even for over 50% of all patients with muscle weakness/pain. Clear guidance is necessary to enable the optimal management of plasma in real-world clinical practice in patients who experience subjective AEs. In this Position Paper of the International Lipid Expert Panel (ILEP), we present a step-by-step patient-centred approach to the identification and management of SAMS with a particular focus on strategies to prevent and manage the nocebo/drucebo effect and to improve long-term compliance with lipid-lowering therapy.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Drucebo effect
- Nocebo effect
- SAMS
- Statin intolerance
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Till lärosätets databas
- Av författaren/redakt...
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Penson, Peter E.
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Bruckert, Eric
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Marais, David
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Reiner, Željko
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Pirro, Matteo
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Sahebkar, Amirho ...
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visa fler...
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Bajraktari, Gani
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Mirrakhimov, Erk ...
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Rizzo, Manfredi
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Mikhailidis, Dim ...
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Sachinidis, Alex ...
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Gaita, Dan
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Latkovskis, Gust ...
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Mazidi, Mohsen
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Toth, Peter P.
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Pella, Daniel
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Alnouri, Fahad
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Postadzhiyan, Ar ...
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Yeh, Hung-I
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Mancini, G.B. Jo ...
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von Haehling, St ...
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Banach, Maciej
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