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Low-protein formula...
Low-protein formulas with alpha-lactalbumin-enriched or glycomacropeptide-reduced whey : effects on growth, nutrient intake and protein metabolism during early infancy
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- Tinghäll Nilsson, Ulrika (författare)
- Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Hernell, Olle (författare)
- Umeå University,Umeå universitet,Pediatrik
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- Lönnerdal, Bo (författare)
- Department of Nutrition, University of California, CA, Davis, United States
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- Hartvigsen, Merete Lindberg (författare)
- Arla Foods Ingredients Group P/S, Viby J, Denmark
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- Jacobsen, Lotte Neergaard (författare)
- Arla Foods Ingredients Group P/S, Viby J, Denmark
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- Kvistgaard, Anne Staudt (författare)
- Arla Foods Ingredients Group P/S, Viby J, Denmark
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- Karlsland Åkeson, Pia (författare)
- Lund University,Lunds universitet,Preventiv pediatrik,Forskargrupper vid Lunds universitet,Preventive Paediatrics,Lund University Research Groups
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(creator_code:org_t)
- 2023-02-17
- 2023
- Engelska.
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Ingår i: Nutrients. - : MDPI. - 2072-6643. ; 15:4
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Protein intake is higher in formula-fed than in breast-fed infants during infancy, which may lead to an increased risk of being overweight. Applying alpha-lactalbumin (α-lac)-enriched whey or casein glycomacropeptide (CGMP)-reduced whey to infant formula may enable further reduction of formula protein by improving the amino acid profile. Growth, nutrient intake, and protein metabolites were evaluated in a randomized, prospective, double-blinded intervention trial where term infants received standard formula (SF:2.2 g protein/100 kcal; n = 83) or low-protein formulas with α-lac-enriched whey (α-lac-EW;1.75 g protein/100 kcal; n = 82) or CGMP-reduced whey (CGMP-RW;1.76 g protein/100 kcal; n = 80) from 2 to 6 months. Breast-fed infants (BF; n = 83) served as reference. Except between 4 and 6 months, when weight gain did not differ between α-lac-EW and BF (p = 0.16), weight gain was higher in all formula groups compared to BF. Blood urea nitrogen did not differ between low-protein formula groups and BF during intervention, but was lower than in SF. Essential amino acids were similar or higher in α-lac-EW and CGMP-RW compared to BF. Conclusion: Low-protein formulas enriched with α-lac-enriched or CGMP-reduced whey supports adequate growth, with more similar weight gain in α-lac-enriched formula group and BF, and with metabolic profiles closer to that of BF infants.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- alpha-lactalbumin
- amino acids
- CGMP
- energetic efficiency
- infant formula
- infant growth
- low protein
- obesity
- protein metabolism
- protein quality
- alpha-lactalbumin
- amino acids
- CGMP
- energetic efficiency
- infant formula
- infant growth
- low protein
- obesity
- protein metabolism
- protein quality
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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