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Sökning: onr:"swepub:oai:DiVA.org:umu-212215" > Is short sleep bad ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00009153naa a2200601 4500
001oai:DiVA.org:umu-212215
003SwePub
008230721s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2122152 URI
0247 a https://doi.org/10.1523/JNEUROSCI.2330-22.20232 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Fjell, Anders M.u Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Computational Radiology and Artificial Intelligence, Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway4 aut
2451 0a Is short sleep bad for the brain? :b Brain structure and cognitive function in short sleepers
264 1c 2023
338 a print2 rdacarrier
520 a Many sleep less than recommended without experiencing daytime sleepiness. According to prevailing views, short sleep increases risk of lower brain health and cognitive function. Chronic mild sleep deprivation could cause undetected sleep debt, negatively affecting cognitive function and brain health. However, it is possible that some have less sleep need and are more resistant to negative effects of sleep loss. We investigated this using a cross-sectional and longitudinal sample of 47,029 participants of both sexes (20-89 years) from the Lifebrain consortium, Human Connectome project (HCP) and UK Biobank (UKB), with measures of self-reported sleep, including 51,295 MRIs of the brain and cognitive tests. A total of 740 participants who reported to sleep <6 h did not experience daytime sleepiness or sleep problems/disturbances interfering with falling or staying asleep. These short sleepers showed significantly larger regional brain volumes than both short sleepers with daytime sleepiness and sleep problems (n = 1742) and participants sleeping the recommended 7-8 h (n = 3886). However, both groups of short sleepers showed slightly lower general cognitive function (GCA), 0.16 and 0.19 SDs, respectively. Analyses using accelerometer-estimated sleep duration confirmed the findings, and the associations remained after controlling for body mass index, depression symptoms, income, and education. The results suggest that some people can cope with less sleep without obvious negative associations with brain morphometry and that sleepiness and sleep problems may be more related to brain structural differences than duration. However, the slightly lower performance on tests of general cognitive abilities warrants closer examination in natural settings.SIGNIFICANCE STATEMENT: Short habitual sleep is prevalent, with unknown consequences for brain health and cognitive performance. Here, we show that daytime sleepiness and sleep problems are more strongly related to regional brain volumes than sleep duration. However, participants sleeping ≤6 h had slightly lower scores on tests of general cognitive function (GCA). This indicates that sleep need is individual and that sleep duration per se is very weakly if at all related brain health, while daytime sleepiness and sleep problems may show somewhat stronger associations. The association between habitual short sleep and lower scores on tests of general cognitive abilities must be further scrutinized in natural settings.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
653 a brain
653 a cognition
653 a hippocampus
653 a MRI
653 a sleep
653 a sleepiness
7001 a Sørensen, Øysteinu Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
7001 a Wang, Yunpengu Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
7001 a Amlien, Inge K.u Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
7001 a Baaré, William F Cu Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Copenhagen, Denmark4 aut
7001 a Bartrés-Faz, Davidu Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain4 aut
7001 a Boraxbekk, Carl-Johan,d 1980-u Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Diagnostisk radiologi,Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Copenhagen, Denmark; Institute of Sports Medicine Copenhagen (ISMC), Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark; Institute for Clinical Medicine, Faculty of Medical and Health Sciences, University of Copenhagen, Copenhagen, Denmark4 aut0 (Swepub:umu)olncan02
7001 a Brandmaier, Andreas M.u Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychology, MSB Medical School Berlin, Berlin, Germany4 aut
7001 a Demuth, Iljau corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Endocrinology and Metabolic Diseases (including Division of Lipid Metabolism), Biology of Aging working group, Charité-Universitätsmedizin BerlinAugustenburger Platz 1, Berlin, Germany; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany; BCRT - Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany4 aut
7001 a Drevon, Christian A.u Vitas AS, The Science Park, Oslo, Norway; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of 0372 Oslo, Norway4 aut
7001 a Ebmeier, Klaus P.u Department of Psychiatry, University of Oxford, Oxford, United Kingdom4 aut
7001 a Ghisletta, Paolou Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland; Swiss National Centre of Competence in Research LIVES, University of Geneva, Geneva, Switzerland4 aut
7001 a Kievit, Rogieru Cognitive Neuroscience Department, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, GA Nijmegen, Netherlands4 aut
7001 a Kühn, Simoneu Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany4 aut
7001 a Madsen, Kathrine Skaku Danish Research Centre for Magnetic Resonance (DRCMR), Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital-Amager and Hvidovre, 2650 Hvidovre, Copenhagen, Denmark; Radiography, Department of Technology, University College Copenhagen, Copenhagen, Denmark4 aut
7001 a Nyberg, Lars,d 1966-u Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för strålningsvetenskaper,Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut0 (Swepub:umu)lany0001
7001 a Solé-Padullés, Cristinau Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain4 aut
7001 a Vidal-Piñeiro, Didacu Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
7001 a Wagner, Gerdu Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany4 aut
7001 a Watne, Leiv Ottou Oslo Delirium Research Group, Oslo University Hospital, Oslo, Norway; Department of Geriatric Medicine, Akershus University Hospital, Norway; Institute of Clinical Medicine, University of Oslo, Campus Ahus, Norway4 aut
7001 a Walhovd, Kristine B.u Computational Radiology and Artificial Intelligence, Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway; Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
7102 a Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Computational Radiology and Artificial Intelligence, Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norwayb Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 org
7730 t Journal of Neuroscienceg 43:28, s. 5241-5250q 43:28<5241-5250x 0270-6474x 1529-2401
8564 u https://doi.org/10.1523/JNEUROSCI.2330-22.2023y Fulltext
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-212215
8564 8u https://doi.org/10.1523/JNEUROSCI.2330-22.2023

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